ID   AKH_PROTE               Reviewed;           8 AA.
AC   P61856; P17975; Q9VZH6;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2004, sequence version 1.
DT   02-JUN-2021, entry version 37.
DE   RecName: Full=Adipokinetic hormone;
DE            Short=AKH;
DE   AltName: Full=Hypertrehalosaemic hormone;
DE            Short=HRTH;
GN   Name=AKH;
OS   Protophormia terraenovae (Northern blowfly) (Lucilia terraenovae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC   Calliphoridae; Chrysomyinae; Protophormia.
OX   NCBI_TaxID=34676;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT TRP-8.
RC   TISSUE=Corpora cardiaca;
RX   PubMed=2386478; DOI=10.1042/bj2690309;
RA   Gaede G., Wilps H., Kellner R.;
RT   "Isolation and structure of a novel charged member of the red-pigment-
RT   concentrating hormone-adipokinetic hormone family of peptides isolated from
RT   the corpora cardiaca of the blowfly Phormia terraenovae (Diptera).";
RL   Biochem. J. 269:309-313(1990).
CC   -!- FUNCTION: Probably causes a marked increase in hemolymph carbohydrate.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; S11545; S11545.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002047; Adipokinetic_hormone_CS.
DR   PROSITE; PS00256; AKH; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..8
FT                   /note="Adipokinetic hormone"
FT                   /id="PRO_0000043443"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:2386478"
FT   MOD_RES         8
FT                   /note="Tryptophan amide"
FT                   /evidence="ECO:0000269|PubMed:2386478"
SQ   SEQUENCE   8 AA;  993 MW;  867AB775B9D1A736 CRC64;
     QLTFSPDW