ID   AKH_ROMMI               Reviewed;           8 AA.
AC   P67786; P14086;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   11-DEC-2019, entry version 33.
DE   RecName: Full=Adipokinetic hormone;
DE            Short=AKH;
DE   AltName: Full=RO II;
OS   Romalea microptera (Eastern lubber grasshopper) (Romalea guttata).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Romaleidae; Romaleinae; Romalea.
OX   NCBI_TaxID=7007;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT TRP-8.
RC   TISSUE=Corpora cardiaca;
RX   PubMed=3226948; DOI=10.1016/0196-9781(88)90107-6;
RA   Gaede G., Hilbich C., Beyreuther K., Rinehart K.L. Jr.;
RT   "Sequence analyses of two neuropeptides of the AKH/RPCH-family from the
RT   lubber grasshopper, Romalea microptera.";
RL   Peptides 9:681-688(1988).
CC   -!- FUNCTION: This hormone, released from cells in the corpora cardiaca,
CC       causes release of diglycerides from the fat body and stimulation of
CC       muscles to use these diglycerides as an energy source during energy-
CC       demanding processes.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007629; P:flight behavior; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002047; Adipokinetic_hormone_CS.
DR   PROSITE; PS00256; AKH; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Flight; Hormone; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..8
FT                   /note="Adipokinetic hormone"
FT                   /id="PRO_0000043424"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:3226948"
FT   MOD_RES         8
FT                   /note="Tryptophan amide"
FT                   /evidence="ECO:0000269|PubMed:3226948"
SQ   SEQUENCE   8 AA;  938 MW;  867861B5B9C452D6 CRC64;
     QVNFSTGW