ID   FIS_PECAS               Reviewed;          98 AA.
AC   Q6DAJ8;
DT   10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
GN   Name=fis {ECO:0000255|HAMAP-Rule:MF_00166}; OrderedLocusNames=ECA0255;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC       upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC       Rule:MF_00166}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC       {ECO:0000255|HAMAP-Rule:MF_00166}.
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DR   EMBL; BX950851; CAG73175.1; -; Genomic_DNA.
DR   RefSeq; WP_005975342.1; NC_004547.2.
DR   AlphaFoldDB; Q6DAJ8; -.
DR   SMR; Q6DAJ8; -.
DR   STRING; 218491.ECA0255; -.
DR   EnsemblBacteria; CAG73175; CAG73175; ECA0255.
DR   GeneID; 51387705; -.
DR   GeneID; 61410542; -.
DR   GeneID; 66800529; -.
DR   KEGG; eca:ECA0255; -.
DR   eggNOG; COG2901; Bacteria.
DR   HOGENOM; CLU_158040_3_0_6; -.
DR   OMA; MVLCEVE; -.
DR   OrthoDB; 1933378at2; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   HAMAP; MF_00166; DNA_binding_Fis; 1.
DR   InterPro; IPR005412; Fis_DNA-bd.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   Pfam; PF02954; HTH_8; 1.
DR   PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR   PRINTS; PR01591; DNABINDNGFIS.
DR   PRINTS; PR01590; HTHFIS.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..98
FT                   /note="DNA-binding protein Fis"
FT                   /id="PRO_0000203882"
FT   DNA_BIND        74..93
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
SQ   SEQUENCE   98 AA;  11169 MW;  58853F7C97A22269 CRC64;
     MFEQRVNSDV LTVSTVNSQA QVTQKPLRDS VKQALKNYFA QLNGQDVSDL YELVLAEVEQ
     PLLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN