ID   FIS_PROVU               Reviewed;          93 AA.
AC   P0CW85; O52534; Q84AP2;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   31-MAY-2011, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
DE   Flags: Fragment;
GN   Name=fis {ECO:0000255|HAMAP-Rule:MF_00166};
OS   Proteus vulgaris.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Proteus.
OX   NCBI_TaxID=585;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9811652; DOI=10.1128/jb.180.22.5932-5946.1998;
RA   Beach M.B., Osuna R.;
RT   "Identification and characterization of the fis operon in enteric
RT   bacteria.";
RL   J. Bacteriol. 180:5932-5946(1998).
CC   -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC       upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC       Rule:MF_00166}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC       {ECO:0000255|HAMAP-Rule:MF_00166}.
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DR   EMBL; AF040379; AAC77885.1; -; Genomic_DNA.
DR   AlphaFoldDB; P0CW85; -.
DR   SMR; P0CW85; -.
DR   STRING; 585.DR95_2015; -.
DR   eggNOG; COG2901; Bacteria.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   HAMAP; MF_00166; DNA_binding_Fis; 1.
DR   InterPro; IPR005412; Fis_DNA-bd.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   Pfam; PF02954; HTH_8; 1.
DR   PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR   PRINTS; PR01591; DNABINDNGFIS.
DR   PRINTS; PR01590; HTHFIS.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..>93
FT                   /note="DNA-binding protein Fis"
FT                   /id="PRO_0000408965"
FT   DNA_BIND        74..93
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
FT   NON_TER         93
SQ   SEQUENCE   93 AA;  10645 MW;  74F7C263C3AB8DF3 CRC64;
     MFEQRVNSDV LTVATVNSQD QVTQKPLRDS VKQALKNYFA QLNGQDVNDL YELVLAEVEQ
     PLLDMVMQYT RGNQTRAAQM MGINRGTLRK KLK