FIS_SALHS
ID FIS_SALHS Reviewed; 98 AA.
AC B4TJV9;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
GN Name=fis {ECO:0000255|HAMAP-Rule:MF_00166}; OrderedLocusNames=SeHA_C3683;
OS Salmonella heidelberg (strain SL476).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=454169;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SL476;
RX PubMed=21602358; DOI=10.1128/jb.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC Rule:MF_00166}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC {ECO:0000255|HAMAP-Rule:MF_00166}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001120; ACF68908.1; -; Genomic_DNA.
DR RefSeq; WP_000462905.1; NC_011083.1.
DR AlphaFoldDB; B4TJV9; -.
DR SMR; B4TJV9; -.
DR GeneID; 8911232; -.
DR KEGG; seh:SeHA_C3683; -.
DR HOGENOM; CLU_158040_3_0_6; -.
DR OMA; MVLCEVE; -.
DR Proteomes; UP000001866; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR HAMAP; MF_00166; DNA_binding_Fis; 1.
DR InterPro; IPR005412; Fis_DNA-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR Pfam; PF02954; HTH_8; 1.
DR PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR PRINTS; PR01591; DNABINDNGFIS.
DR PRINTS; PR01590; HTHFIS.
DR SUPFAM; SSF46689; SSF46689; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..98
FT /note="DNA-binding protein Fis"
FT /id="PRO_1000097461"
FT DNA_BIND 74..93
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
SQ SEQUENCE 98 AA; 11240 MW; 2E339BFCFCDB163C CRC64;
MFEQRVNSDV LTVSTVNSQD QVTQKPLRDS VKQALKNYFA QLNGQDVNDL YELVLAEVEQ
PLLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN