FIS_SHELP
ID FIS_SHELP Reviewed; 101 AA.
AC A3Q9Q3;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 17-APR-2007, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
GN Name=fis {ECO:0000255|HAMAP-Rule:MF_00166}; OrderedLocusNames=Shew_0329;
OS Shewanella loihica (strain ATCC BAA-1088 / PV-4).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=323850;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1088 / PV-4;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G.,
RA Fredrickson J., Tiedje J., Richardson P.;
RT "Complete sequence of Shewanella loihica PV-4.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC Rule:MF_00166}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC {ECO:0000255|HAMAP-Rule:MF_00166}.
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DR EMBL; CP000606; ABO22201.1; -; Genomic_DNA.
DR RefSeq; WP_011864135.1; NC_009092.1.
DR AlphaFoldDB; A3Q9Q3; -.
DR SMR; A3Q9Q3; -.
DR STRING; 323850.Shew_0329; -.
DR EnsemblBacteria; ABO22201; ABO22201; Shew_0329.
DR KEGG; slo:Shew_0329; -.
DR eggNOG; COG2901; Bacteria.
DR HOGENOM; CLU_158040_3_3_6; -.
DR OMA; MVLCEVE; -.
DR OrthoDB; 1933378at2; -.
DR Proteomes; UP000001558; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR HAMAP; MF_00166; DNA_binding_Fis; 1.
DR InterPro; IPR005412; Fis_DNA-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR Pfam; PF02954; HTH_8; 1.
DR PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR PRINTS; PR01591; DNABINDNGFIS.
DR PRINTS; PR01590; HTHFIS.
DR SUPFAM; SSF46689; SSF46689; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..101
FT /note="DNA-binding protein Fis"
FT /id="PRO_1000023339"
FT DNA_BIND 77..96
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
SQ SEQUENCE 101 AA; 11407 MW; 2FFF7B7492692424 CRC64;
MFDQTTQPEA HQLTVGKIET ANGTIKPQLL RDAVKRAVTN FFAQMDGQEA EEVYEMVLCE
VEAPLLDIIM QHTRGNQTRA ANMLGINRGT LRKKLKKYGM N