ID   FIS_TOLAT               Reviewed;          99 AA.
AC   C4LAF3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
GN   Name=fis {ECO:0000255|HAMAP-Rule:MF_00166}; OrderedLocusNames=Tola_2534;
OS   Tolumonas auensis (strain DSM 9187 / TA4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Tolumonas.
OX   NCBI_TaxID=595494;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 9187 / TA4;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S.,
RA   Beller H.;
RT   "Complete sequence of Tolumonas auensis DSM 9187.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC       upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC       Rule:MF_00166}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC       {ECO:0000255|HAMAP-Rule:MF_00166}.
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DR   EMBL; CP001616; ACQ94128.1; -; Genomic_DNA.
DR   RefSeq; WP_015879577.1; NC_012691.1.
DR   AlphaFoldDB; C4LAF3; -.
DR   SMR; C4LAF3; -.
DR   STRING; 595494.Tola_2534; -.
DR   EnsemblBacteria; ACQ94128; ACQ94128; Tola_2534.
DR   KEGG; tau:Tola_2534; -.
DR   eggNOG; COG2901; Bacteria.
DR   HOGENOM; CLU_158040_3_0_6; -.
DR   OMA; MVLCEVE; -.
DR   OrthoDB; 1933378at2; -.
DR   Proteomes; UP000009073; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   HAMAP; MF_00166; DNA_binding_Fis; 1.
DR   InterPro; IPR005412; Fis_DNA-bd.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   Pfam; PF02954; HTH_8; 1.
DR   PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR   PRINTS; PR01591; DNABINDNGFIS.
DR   PRINTS; PR01590; HTHFIS.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..99
FT                   /note="DNA-binding protein Fis"
FT                   /id="PRO_1000203635"
FT   DNA_BIND        75..94
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
SQ   SEQUENCE   99 AA;  11234 MW;  2A9BF26A7F9EEAFF CRC64;
     MLDQTLTSEA LVTTVTHAQT HQPVQRPLRD SVQQALRNYL AQLNGQDVAE LYDMVLSEVE
     APMLDIIMQY TRGNQTRAAI MMGINRGTLR KKLKKYGMN