ID   FIXA_ECOLU              Reviewed;         256 AA.
AC   B7N7R6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Protein FixA {ECO:0000255|HAMAP-Rule:MF_01055};
GN   Name=fixA {ECO:0000255|HAMAP-Rule:MF_01055}; OrderedLocusNames=ECUMN_0043;
OS   Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585056;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UMN026 / ExPEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Required for anaerobic carnitine reduction. May bring
CC       reductant to CaiA. {ECO:0000255|HAMAP-Rule:MF_01055}.
CC   -!- PATHWAY: Amine and polyamine metabolism; carnitine metabolism.
CC       {ECO:0000255|HAMAP-Rule:MF_01055}.
CC   -!- SUBUNIT: Heterodimer of FixA and FixB. {ECO:0000255|HAMAP-
CC       Rule:MF_01055}.
CC   -!- SIMILARITY: Belongs to the ETF beta-subunit/FixA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01055}.
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DR   EMBL; CU928163; CAR11266.1; -; Genomic_DNA.
DR   RefSeq; WP_000692223.1; NC_011751.1.
DR   RefSeq; YP_002410821.1; NC_011751.1.
DR   AlphaFoldDB; B7N7R6; -.
DR   SMR; B7N7R6; -.
DR   STRING; 585056.ECUMN_0043; -.
DR   EnsemblBacteria; CAR11266; CAR11266; ECUMN_0043.
DR   KEGG; eum:ECUMN_0043; -.
DR   PATRIC; fig|585056.7.peg.230; -.
DR   HOGENOM; CLU_060196_2_2_6; -.
DR   OMA; ADLNEWD; -.
DR   UniPathway; UPA00117; -.
DR   Proteomes; UP000007097; Chromosome.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0009437; P:carnitine metabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd01714; ETF_beta; 1.
DR   Gene3D; 3.40.50.620; -; 1.
DR   HAMAP; MF_01055; FixA; 1.
DR   InterPro; IPR000049; ET-Flavoprotein_bsu_CS.
DR   InterPro; IPR014730; ETF_a/b_N.
DR   InterPro; IPR012255; ETF_b.
DR   InterPro; IPR033948; ETF_beta_N.
DR   InterPro; IPR023463; FixA.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR21294; PTHR21294; 1.
DR   Pfam; PF01012; ETF; 1.
DR   PIRSF; PIRSF000090; Beta-ETF; 1.
DR   SMART; SM00893; ETF; 1.
DR   PROSITE; PS01065; ETF_BETA; 1.
PE   3: Inferred from homology;
KW   Electron transport; Transport.
FT   CHAIN           1..256
FT                   /note="Protein FixA"
FT                   /id="PRO_1000136318"
SQ   SEQUENCE   256 AA;  27186 MW;  1EF66846403A8BC0 CRC64;
     MKIITCYKCV PDEQDIAVNN ADGSLDFSKA DAKISQYDLN AIEAACQLKQ QAAEAQVTAL
     SVGGKALTNA KGRKDVLSRG PDELIVVIDD QFERALPQQT ATALAAAAQK AGFDLILCGD
     GSSDLYAQQV GLLVGEILNI PAVNGVSKII SLTADTLTVE RELEDETETL SIPLPAVVAV
     STDINSPQIP SMKAILGAAK KPVQVWSAAD IGFNAEAAWS EQQVAAPKQR ERQRIVIEGD
     GEEQIAAFAE NLRKVI