ID   FIXA_SALTI              Reviewed;         256 AA.
AC   Q8Z9L0;
DT   09-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Protein FixA {ECO:0000255|HAMAP-Rule:MF_01055};
GN   Name=fixA {ECO:0000255|HAMAP-Rule:MF_01055};
GN   OrderedLocusNames=STY0085, t0076;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Required for anaerobic carnitine reduction. May bring
CC       reductant to CaiA. {ECO:0000255|HAMAP-Rule:MF_01055}.
CC   -!- PATHWAY: Amine and polyamine metabolism; carnitine metabolism.
CC       {ECO:0000255|HAMAP-Rule:MF_01055}.
CC   -!- SUBUNIT: Heterodimer of FixA and FixB. {ECO:0000255|HAMAP-
CC       Rule:MF_01055}.
CC   -!- SIMILARITY: Belongs to the ETF beta-subunit/FixA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01055}.
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DR   EMBL; AL513382; CAD01229.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO67809.1; -; Genomic_DNA.
DR   RefSeq; NP_454685.1; NC_003198.1.
DR   RefSeq; WP_000692187.1; NZ_QXGZ01000033.1.
DR   AlphaFoldDB; Q8Z9L0; -.
DR   SMR; Q8Z9L0; -.
DR   STRING; 220341.16501358; -.
DR   EnsemblBacteria; AAO67809; AAO67809; t0076.
DR   KEGG; stt:t0076; -.
DR   KEGG; sty:STY0085; -.
DR   PATRIC; fig|220341.7.peg.85; -.
DR   eggNOG; COG2086; Bacteria.
DR   HOGENOM; CLU_060196_2_2_6; -.
DR   OMA; ADLNEWD; -.
DR   UniPathway; UPA00117; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0009437; P:carnitine metabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd01714; ETF_beta; 1.
DR   Gene3D; 3.40.50.620; -; 1.
DR   HAMAP; MF_01055; FixA; 1.
DR   InterPro; IPR000049; ET-Flavoprotein_bsu_CS.
DR   InterPro; IPR014730; ETF_a/b_N.
DR   InterPro; IPR012255; ETF_b.
DR   InterPro; IPR033948; ETF_beta_N.
DR   InterPro; IPR023463; FixA.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR21294; PTHR21294; 1.
DR   Pfam; PF01012; ETF; 1.
DR   PIRSF; PIRSF000090; Beta-ETF; 1.
DR   SMART; SM00893; ETF; 1.
DR   PROSITE; PS01065; ETF_BETA; 1.
PE   3: Inferred from homology;
KW   Electron transport; Transport.
FT   CHAIN           1..256
FT                   /note="Protein FixA"
FT                   /id="PRO_0000167896"
SQ   SEQUENCE   256 AA;  27252 MW;  D284763B42D24B17 CRC64;
     MKIITCYKCV PDEQDIAINN ADGTLDFSKA DSKISQYDLN AIEAACQLKQ QLGDAQVVAM
     SVGGKALTNA KGRKDVLSRG PDELIVVIDD QFEQALPQHT ATALAAAAQK SGFDLLICGD
     GSSDLYAQQV GLLVGEALNI PAINGVSKIL SLTDSTLTVE RELEDEVETL SIPLPAVIAV
     STDINTPQIP SMKAILGAAK KPVQVWSPAD IGLNSVPAYS TQQVAAPKQR ERQRVVIEGD
     GEEQIAAFVE NLRKII