ID   FIXC_RHIME              Reviewed;         435 AA.
AC   P09820;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Protein FixC;
GN   Name=fixC; OrderedLocusNames=RA0445; ORFNames=SMa0817;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymA (megaplasmid 1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=3029021; DOI=10.1128/jb.169.3.1127-1136.1987;
RA   Earl C.D., Ronson C.W., Ausubel F.M.;
RT   "Genetic and structural analysis of the Rhizobium meliloti fixA, fixB,
RT   fixC, and fixX genes.";
RL   J. Bacteriol. 169:1127-1136(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481432; DOI=10.1073/pnas.161294798;
RA   Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F.,
RA   Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L.,
RA   Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H., Palm C.,
RA   Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A.,
RA   Long S.R.;
RT   "Nucleotide sequence and predicted functions of the entire Sinorhizobium
RT   meliloti pSymA megaplasmid.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Could be required for the formation of a functional
CC       nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and
CC       reduces a quinone.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the ETF-QO/FixC family. {ECO:0000305}.
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DR   EMBL; M15546; AAA21770.1; -; Genomic_DNA.
DR   EMBL; AE006469; AAK65103.1; -; Genomic_DNA.
DR   PIR; C26952; C26952.
DR   PIR; E95317; E95317.
DR   RefSeq; NP_435691.1; NC_003037.1.
DR   RefSeq; WP_003532765.1; NC_003037.1.
DR   AlphaFoldDB; P09820; -.
DR   SMR; P09820; -.
DR   EnsemblBacteria; AAK65103; AAK65103; SMa0817.
DR   GeneID; 25011418; -.
DR   GeneID; 61599256; -.
DR   KEGG; sme:SMa0817; -.
DR   PATRIC; fig|266834.11.peg.458; -.
DR   HOGENOM; CLU_050977_0_0_5; -.
DR   OMA; GEWAVRI; -.
DR   PRO; PR:P09820; -.
DR   Proteomes; UP000001976; Plasmid pSymA.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR039651; FixC-like.
DR   PANTHER; PTHR43624; PTHR43624; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Nitrogen fixation; Oxidoreductase; Plasmid;
KW   Reference proteome.
FT   CHAIN           1..435
FT                   /note="Protein FixC"
FT                   /id="PRO_0000200688"
SQ   SEQUENCE   435 AA;  47288 MW;  2B7B1067093786C8 CRC64;
     MTKEKFDAIV VGAGMSGNAA AYAMASRGLK VLQLERGEYP GSKNVQGAIM YANMLEAIIP
     DFRNDAPLER HLVEQRFWIM DDTSHTGMHY RSDDFNEVTP NRYTIIRAQF DKWLSRKVCE
     AGGTVLCETT ATGLEWDSAG KAIGVRTDRA GDVVLADVVV LAEGVNGLLG TRAGLREMPK
     SKNVALAVKE LHFLPEEVIA ERFGLTGDEG CVIEAGGTIS RGMAGLGFLY TNKESISLGI
     GCLISNFAET MERPYALLDA FKRHPSIQPL IAGSEVKEYA AHLIPEGGFN AIPRLCGNGW
     VVVGDAAQLN NAVHREGSNL AMASGRMAGE AISIIKSRGG VMDKASLSLY KTMLDKSFVV
     EDLSKQKDMP SLLHTNSPNF FTTYPQLISH AAQNFVRVDG TPKIEREIAT TAAFLRARSR
     WGLVSDAVRL ASAWR