ID   FIXH_RHIME              Reviewed;         167 AA.
AC   P18397;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Nitrogen fixation protein FixH;
GN   Name=fixH; OrderedLocusNames=RA0660; ORFNames=SMa1210;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymA (megaplasmid 1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=RCR2011 / SU47;
RX   PubMed=2536685; DOI=10.1128/jb.171.2.929-939.1989;
RA   Kahn D., David M., Domergue O., Daveran M.-L., Ghai J., Hirsch P.R.,
RA   Batut J.;
RT   "Rhizobium meliloti fixGHI sequence predicts involvement of a specific
RT   cation pump in symbiotic nitrogen fixation.";
RL   J. Bacteriol. 171:929-939(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481432; DOI=10.1073/pnas.161294798;
RA   Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F.,
RA   Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L.,
RA   Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H., Palm C.,
RA   Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A.,
RA   Long S.R.;
RT   "Nucleotide sequence and predicted functions of the entire Sinorhizobium
RT   meliloti pSymA megaplasmid.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: The four proteins FixG, FixH, FixI, and FixS may participate
CC       in a membrane-bound complex coupling the FixI cation pump with a redox
CC       process catalyzed by FixG.
CC   -!- SUBCELLULAR LOCATION: Cell membrane.
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DR   EMBL; Z21854; CAA79906.1; -; Genomic_DNA.
DR   EMBL; AE006469; AAK65318.1; -; Genomic_DNA.
DR   PIR; B32052; B32052.
DR   PIR; D95344; D95344.
DR   RefSeq; NP_435906.1; NC_003037.1.
DR   RefSeq; WP_010967639.1; NC_003037.1.
DR   AlphaFoldDB; P18397; -.
DR   SMR; P18397; -.
DR   EnsemblBacteria; AAK65318; AAK65318; SMa1210.
DR   GeneID; 25011568; -.
DR   GeneID; 61599428; -.
DR   KEGG; sme:SMa1210; -.
DR   PATRIC; fig|266834.11.peg.680; -.
DR   HOGENOM; CLU_111458_2_0_5; -.
DR   OMA; GNWNIRM; -.
DR   PRO; PR:P18397; -.
DR   Proteomes; UP000001976; Plasmid pSymA.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   InterPro; IPR008620; FixH.
DR   InterPro; IPR018037; FixH_proteobacterial.
DR   Pfam; PF05751; FixH; 1.
DR   PIRSF; PIRSF011386; FixH; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Nitrogen fixation; Plasmid; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..167
FT                   /note="Nitrogen fixation protein FixH"
FT                   /id="PRO_0000087260"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   167 AA;  18510 MW;  828F9A254E415FB0 CRC64;
     MSTATKQRSP KRGFTGWHMV AVMSLFFGTV ISVNLVMAWN ASRSWSGLVV ENTYVASQQF
     NGKVAEGRAF QASGIKGRLT TEPGAIRYVL TRNGEPEQKI DKVIAVLKRP VEEHEDLRVE
     LHPRGEGAFV LAEELKPGQW IAAMMAMAGD AVVHRQTIRF IAEGRDK