ID   AKIRA_XENLA             Reviewed;         186 AA.
AC   Q5FWN7;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 38.
DE   RecName: Full=Akirin-1A;
GN   Name=akirin1-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Molecular adapter that acts as a bridge between proteins, and
CC       which is involved skeletal muscle development. Functions as signal
CC       transducer for MSTN during skeletal muscle regeneration and myogenesis.
CC       {ECO:0000250|UniProtKB:Q99LF1}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9H9L7}.
CC   -!- SIMILARITY: Belongs to the akirin family. {ECO:0000305}.
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DR   EMBL; BC089268; AAH89268.1; -; mRNA.
DR   RefSeq; NP_001089245.1; NM_001095776.1.
DR   AlphaFoldDB; Q5FWN7; -.
DR   SMR; Q5FWN7; -.
DR   MaxQB; Q5FWN7; -.
DR   DNASU; 734292; -.
DR   GeneID; 734292; -.
DR   KEGG; xla:734292; -.
DR   CTD; 734292; -.
DR   Xenbase; XB-GENE-5820134; akirin1.S.
DR   OrthoDB; 1420469at2759; -.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 734292; Expressed in blastula and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISS:UniProtKB.
DR   InterPro; IPR024132; Akirin.
DR   PANTHER; PTHR13293; PTHR13293; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..186
FT                   /note="Akirin-1A"
FT                   /id="PRO_0000274320"
FT   REGION          14..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           183..186
FT                   /note="SYVS motif"
FT                   /evidence="ECO:0000250|UniProtKB:Q53H80"
FT   COMPBIAS        43..60
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   186 AA;  21129 MW;  EB67E60FD46A5FBA CRC64;
     MACGATLKRS MEFEALMSPQ SPKRRRCAPL PGSPATPSPQ RCAIRPEMQQ GQQQPLSQLG
     GDRRLTPEQI LQNIKQEYTR YQRRRQLEGA FNQCEAGALN EVQASCSSLT APSSPGSLVK
     KDQPTFSLRQ VGILCERLLK DHEDKIREEY EQILNIKLAE QYESFVKFTH DQIMRRYGAR
     PASYVS