FK102_ARATH
ID FK102_ARATH Reviewed; 402 AA.
AC Q1PE10; Q8LGB0; Q9SV99;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=F-box/kelch-repeat protein At4g39590;
GN OrderedLocusNames=At4g39590; ORFNames=F23K16.220;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM60949.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB44694.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB80622.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AL078620; CAB44694.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL161595; CAB80622.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002687; AEE87091.1; -; Genomic_DNA.
DR EMBL; AY084368; AAM60949.1; ALT_INIT; mRNA.
DR EMBL; DQ446908; ABE66121.1; -; mRNA.
DR PIR; T09375; T09375.
DR RefSeq; NP_568062.1; NM_120119.3.
DR AlphaFoldDB; Q1PE10; -.
DR SMR; Q1PE10; -.
DR PaxDb; Q1PE10; -.
DR PRIDE; Q1PE10; -.
DR ProteomicsDB; 230102; -.
DR EnsemblPlants; AT4G39590.1; AT4G39590.1; AT4G39590.
DR GeneID; 830113; -.
DR Gramene; AT4G39590.1; AT4G39590.1; AT4G39590.
DR KEGG; ath:AT4G39590; -.
DR Araport; AT4G39590; -.
DR TAIR; locus:2122516; AT4G39590.
DR eggNOG; KOG1072; Eukaryota.
DR HOGENOM; CLU_032521_1_2_1; -.
DR InParanoid; Q1PE10; -.
DR OMA; NNTHWFT; -.
DR OrthoDB; 651274at2759; -.
DR PhylomeDB; Q1PE10; -.
DR PRO; PR:Q1PE10; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q1PE10; baseline and differential.
DR Genevisible; Q1PE10; AT.
DR Gene3D; 2.120.10.80; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00612; Kelch; 1.
DR SUPFAM; SSF117281; SSF117281; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 2: Evidence at transcript level;
KW Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..402
FT /note="F-box/kelch-repeat protein At4g39590"
FT /id="PRO_0000283260"
FT DOMAIN 35..81
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REPEAT 143..198
FT /note="Kelch 1"
FT REPEAT 199..246
FT /note="Kelch 2"
FT REPEAT 255..300
FT /note="Kelch 3"
FT REPEAT 302..341
FT /note="Kelch 4"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 26
FT /note="E -> Q (in Ref. 3; AAM60949)"
FT /evidence="ECO:0000305"
FT CONFLICT 114
FT /note="R -> Q (in Ref. 3; AAM60949)"
FT /evidence="ECO:0000305"
FT CONFLICT 129
FT /note="Y -> H (in Ref. 3; AAM60949)"
FT /evidence="ECO:0000305"
FT CONFLICT 223
FT /note="T -> I (in Ref. 3; AAM60949)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 402 AA; 45744 MW; 38645829EE356ACC CRC64;
MFPMSSTSRS SAANNRKDPP RKKNKETPSP VTREPTSIDS LPNDLLLNCF ARVSRMYYPA
LSRVSKRFRS IVTSPEIYNT RSLLNRTEKC LYLCLRFPFD NNTHWFTLYQ NPNRTVSDKV
FLQIPSPQYP LTLSSNLVAV GSNIYRIGGT VGDDSCPLGF DREPSSKVSI LDCRSHTWRD
GPRMRLNRRS STTSVVDGKI YVTGGTEDTD NPSHWIEVFD PKTQSWGTVT NPHIVKVWEE
VCYRRAVKSI GHDGKLYLSG DKYVVYDPDE GKWNSVEEHW LIGYAIGSSN CVVDNILFYW
DQGVFKWYDS KVSSWKQLKG LEGLPDDFSQ REYCKLVDLG GKMAVLWDKW EYSGVCMIFC
AEISLEKRDG DEIWGKVEWF DTVLEVGASC SLKSADALSA SV
