FK104_ARATH
ID FK104_ARATH Reviewed; 390 AA.
AC Q1PE09; Q8LEQ6; Q9LDK6;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=F-box/kelch-repeat protein At4g39753;
GN OrderedLocusNames=At4g39753; ORFNames=T19P19.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB77062.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g39750 has been split into 3 genes: At4g39750, At4g39753 and At4g39756.; Evidence={ECO:0000305};
CC Sequence=CAB80638.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g39750 has been split into 3 genes: At4g39750, At4g39753 and At4g39756.; Evidence={ECO:0000305};
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DR EMBL; AL022605; CAB77062.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161595; CAB80638.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE87114.1; -; Genomic_DNA.
DR EMBL; DQ446909; ABE66122.1; -; mRNA.
DR EMBL; AY085293; AAM62525.1; -; mRNA.
DR EMBL; BT029018; ABI93927.1; -; mRNA.
DR PIR; H85470; H85470.
DR PIR; T05012; T05012.
DR RefSeq; NP_568070.1; NM_120137.2.
DR AlphaFoldDB; Q1PE09; -.
DR SMR; Q1PE09; -.
DR BioGRID; 15412; 2.
DR IntAct; Q1PE09; 2.
DR PaxDb; Q1PE09; -.
DR PRIDE; Q1PE09; -.
DR EnsemblPlants; AT4G39753.1; AT4G39753.1; AT4G39753.
DR GeneID; 830132; -.
DR Gramene; AT4G39753.1; AT4G39753.1; AT4G39753.
DR KEGG; ath:AT4G39753; -.
DR Araport; AT4G39753; -.
DR TAIR; locus:505006571; AT4G39753.
DR eggNOG; KOG1072; Eukaryota.
DR HOGENOM; CLU_032521_1_2_1; -.
DR InParanoid; Q1PE09; -.
DR OMA; ETESANW; -.
DR OrthoDB; 1016360at2759; -.
DR PhylomeDB; Q1PE09; -.
DR PRO; PR:Q1PE09; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q1PE09; baseline and differential.
DR Genevisible; Q1PE09; AT.
DR Gene3D; 2.120.10.80; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF117281; SSF117281; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
PE 2: Evidence at transcript level;
KW Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..390
FT /note="F-box/kelch-repeat protein At4g39753"
FT /id="PRO_0000274963"
FT DOMAIN 32..79
FT /note="F-box"
FT REPEAT 139..192
FT /note="Kelch 1"
FT REPEAT 193..243
FT /note="Kelch 2"
FT REPEAT 245..286
FT /note="Kelch 3"
FT REPEAT 288..321
FT /note="Kelch 4"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 35
FT /note="L -> F (in Ref. 3; AAM62525)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 390 AA; 44958 MW; 66CC701B7E2F1399 CRC64;
MVTFWAETAA SAATTSKGEP PSKKRKTNPS PPPSLLSLPD VLILNCLSRI PKSYYPKLSI
VSKTFRDLII SIDLNHARFH HKTQEHFFHV CLKLPDRPLP SWYTLWIKPQ GFDDKEEEKK
KKKKSTLVQV PSSYASQTPL LVVGIDSDVY AFKQCYPPSR VMFVRNKECV IWRNAPDMTV
ARANPVAYVF DRKIYVMGGC AETESANWGE VFDPKTQTWE PLPVPSPELR FSSMIRKIEM
IQGKFYVRSN DSKDSVYDPI REKWNVAAKP QLNDSRCSVG NVWYSCRPNS FLWFDNEIKN
WRLIKGLSSL NHSCRSGLIE TVCYDGNLLL LWDKPTKPRR RVCEDKYICC ALISFNKRKN
GQVWGKVEWS NVVLTVPSSY RFLRSTVIRT
