FK117_ARATH
ID FK117_ARATH Reviewed; 563 AA.
AC Q9FII2; Q8VXV3;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=F-box/kelch-repeat protein At5g42350;
GN OrderedLocusNames=At5g42350; ORFNames=MDH9.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
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DR EMBL; AB016888; BAB10476.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94799.1; -; Genomic_DNA.
DR EMBL; AY074568; AAL67108.1; -; mRNA.
DR EMBL; AF436832; AAL32014.1; -; mRNA.
DR EMBL; BT010181; AAQ22650.1; -; mRNA.
DR RefSeq; NP_199050.1; NM_123600.3.
DR AlphaFoldDB; Q9FII2; -.
DR SMR; Q9FII2; -.
DR BioGRID; 19491; 4.
DR STRING; 3702.AT5G42350.1; -.
DR PaxDb; Q9FII2; -.
DR PRIDE; Q9FII2; -.
DR ProteomicsDB; 232085; -.
DR EnsemblPlants; AT5G42350.1; AT5G42350.1; AT5G42350.
DR GeneID; 834241; -.
DR Gramene; AT5G42350.1; AT5G42350.1; AT5G42350.
DR KEGG; ath:AT5G42350; -.
DR Araport; AT5G42350; -.
DR TAIR; locus:2162286; AT5G42350.
DR eggNOG; ENOG502QQKY; Eukaryota.
DR HOGENOM; CLU_033597_0_0_1; -.
DR InParanoid; Q9FII2; -.
DR OMA; MRREGSY; -.
DR OrthoDB; 732544at2759; -.
DR PhylomeDB; Q9FII2; -.
DR PRO; PR:Q9FII2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FII2; baseline and differential.
DR Genevisible; Q9FII2; AT.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IPI:TAIR.
DR GO; GO:0001558; P:regulation of cell growth; IMP:TAIR.
DR GO; GO:0008361; P:regulation of cell size; IMP:TAIR.
DR Gene3D; 2.120.10.80; -; 2.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF117281; SSF117281; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 2: Evidence at transcript level;
KW Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..563
FT /note="F-box/kelch-repeat protein At5g42350"
FT /id="PRO_0000283272"
FT DOMAIN 129..175
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REPEAT 184..231
FT /note="Kelch 1"
FT REPEAT 232..282
FT /note="Kelch 2"
FT REPEAT 355..402
FT /note="Kelch 3"
FT CONFLICT 453
FT /note="L -> F (in Ref. 3; AAL67108)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 563 AA; 64726 MW; 127E86EED0854904 CRC64;
MMISEKPLGV EESIRQDLEV LTVSRRLVKS VSQKLKKKIH KTEVVEDEEI ARGAVNCLSI
SVGCRVADTG EDFEDSSNKR WSSASEEGKG LMTICGTEET RLDCFSYGVR ERFWKKNNRK
YLADSGQDYR KHVYLPDDIL EMCLMRLPLT SLLNAHLVCK KWQSMANTQR FLQMRREGSF
QTPWLFLFAA LKDGCSSGDI HGYDVSQDKW HRIETDLLKG RFMYSVTSIH EEIYIVGGRS
MDRNSFKSHR GILVFSPSIK AWRKIASMRH ARSLPIVGAT EVTSEFSTMQ TKQNRQDRRF
HLSRVGGESD VYEDPHRLSV RRQNRNSADQ NGTKSHRLIR QKLDRLNRNS SKRFVLIAIG
GTGLFDEPLD SGEIYDSATN TWSEMQRLPM GFGVVSCGII CNGIFYAYSE NDKLSGYDIE
RGFWITIQTS PIPPRVHEFY PKLVSCNHRL FMLSVSWCDE GDGQIGRRNK AVRKLWELDL
VYLTWTEVSV HPDAPMDWNA TYVSDQNILM GIEMFKIFGQ VLSFFTVCDV LTEEASWRHV
SRNQRSQKLN LSCTNKTIAL LHL