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FK117_ARATH
ID   FK117_ARATH             Reviewed;         563 AA.
AC   Q9FII2; Q8VXV3;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=F-box/kelch-repeat protein At5g42350;
GN   OrderedLocusNames=At5g42350; ORFNames=MDH9.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA   Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT   features of the regions of 1,081,958 bp covered by seventeen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:379-391(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
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DR   EMBL; AB016888; BAB10476.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED94799.1; -; Genomic_DNA.
DR   EMBL; AY074568; AAL67108.1; -; mRNA.
DR   EMBL; AF436832; AAL32014.1; -; mRNA.
DR   EMBL; BT010181; AAQ22650.1; -; mRNA.
DR   RefSeq; NP_199050.1; NM_123600.3.
DR   AlphaFoldDB; Q9FII2; -.
DR   SMR; Q9FII2; -.
DR   BioGRID; 19491; 4.
DR   STRING; 3702.AT5G42350.1; -.
DR   PaxDb; Q9FII2; -.
DR   PRIDE; Q9FII2; -.
DR   ProteomicsDB; 232085; -.
DR   EnsemblPlants; AT5G42350.1; AT5G42350.1; AT5G42350.
DR   GeneID; 834241; -.
DR   Gramene; AT5G42350.1; AT5G42350.1; AT5G42350.
DR   KEGG; ath:AT5G42350; -.
DR   Araport; AT5G42350; -.
DR   TAIR; locus:2162286; AT5G42350.
DR   eggNOG; ENOG502QQKY; Eukaryota.
DR   HOGENOM; CLU_033597_0_0_1; -.
DR   InParanoid; Q9FII2; -.
DR   OMA; MRREGSY; -.
DR   OrthoDB; 732544at2759; -.
DR   PhylomeDB; Q9FII2; -.
DR   PRO; PR:Q9FII2; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FII2; baseline and differential.
DR   Genevisible; Q9FII2; AT.
DR   GO; GO:0019005; C:SCF ubiquitin ligase complex; IPI:TAIR.
DR   GO; GO:0001558; P:regulation of cell growth; IMP:TAIR.
DR   GO; GO:0008361; P:regulation of cell size; IMP:TAIR.
DR   Gene3D; 2.120.10.80; -; 2.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF01344; Kelch_1; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SMART; SM00612; Kelch; 2.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..563
FT                   /note="F-box/kelch-repeat protein At5g42350"
FT                   /id="PRO_0000283272"
FT   DOMAIN          129..175
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          184..231
FT                   /note="Kelch 1"
FT   REPEAT          232..282
FT                   /note="Kelch 2"
FT   REPEAT          355..402
FT                   /note="Kelch 3"
FT   CONFLICT        453
FT                   /note="L -> F (in Ref. 3; AAL67108)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   563 AA;  64726 MW;  127E86EED0854904 CRC64;
     MMISEKPLGV EESIRQDLEV LTVSRRLVKS VSQKLKKKIH KTEVVEDEEI ARGAVNCLSI
     SVGCRVADTG EDFEDSSNKR WSSASEEGKG LMTICGTEET RLDCFSYGVR ERFWKKNNRK
     YLADSGQDYR KHVYLPDDIL EMCLMRLPLT SLLNAHLVCK KWQSMANTQR FLQMRREGSF
     QTPWLFLFAA LKDGCSSGDI HGYDVSQDKW HRIETDLLKG RFMYSVTSIH EEIYIVGGRS
     MDRNSFKSHR GILVFSPSIK AWRKIASMRH ARSLPIVGAT EVTSEFSTMQ TKQNRQDRRF
     HLSRVGGESD VYEDPHRLSV RRQNRNSADQ NGTKSHRLIR QKLDRLNRNS SKRFVLIAIG
     GTGLFDEPLD SGEIYDSATN TWSEMQRLPM GFGVVSCGII CNGIFYAYSE NDKLSGYDIE
     RGFWITIQTS PIPPRVHEFY PKLVSCNHRL FMLSVSWCDE GDGQIGRRNK AVRKLWELDL
     VYLTWTEVSV HPDAPMDWNA TYVSDQNILM GIEMFKIFGQ VLSFFTVCDV LTEEASWRHV
     SRNQRSQKLN LSCTNKTIAL LHL
 
 
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