FK122_ARATH
ID FK122_ARATH Reviewed; 372 AA.
AC Q9FI70; Q8GY04;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=F-box/kelch-repeat protein At5g49000;
GN OrderedLocusNames=At5g49000; ORFNames=K19E20.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10470850; DOI=10.1093/dnares/6.3.183;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Kotani H.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence
RT features of the regions of 1,011,550 bp covered by seventeen P1 and TAC
RT clones.";
RL DNA Res. 6:183-195(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9FI70-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9FI70-2; Sequence=VSP_024432;
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DR EMBL; AB017061; BAB10324.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95754.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95755.1; -; Genomic_DNA.
DR EMBL; AK117938; BAC42576.2; -; mRNA.
DR EMBL; BT029493; ABL66750.1; -; mRNA.
DR RefSeq; NP_001119398.1; NM_001125926.2. [Q9FI70-1]
DR RefSeq; NP_199711.2; NM_124277.2. [Q9FI70-2]
DR AlphaFoldDB; Q9FI70; -.
DR SMR; Q9FI70; -.
DR BioGRID; 20205; 9.
DR IntAct; Q9FI70; 10.
DR STRING; 3702.AT5G49000.2; -.
DR PaxDb; Q9FI70; -.
DR PRIDE; Q9FI70; -.
DR EnsemblPlants; AT5G49000.1; AT5G49000.1; AT5G49000. [Q9FI70-2]
DR EnsemblPlants; AT5G49000.2; AT5G49000.2; AT5G49000. [Q9FI70-1]
DR GeneID; 834959; -.
DR Gramene; AT5G49000.1; AT5G49000.1; AT5G49000. [Q9FI70-2]
DR Gramene; AT5G49000.2; AT5G49000.2; AT5G49000. [Q9FI70-1]
DR KEGG; ath:AT5G49000; -.
DR Araport; AT5G49000; -.
DR TAIR; locus:2154404; AT5G49000.
DR eggNOG; KOG1072; Eukaryota.
DR HOGENOM; CLU_032521_1_2_1; -.
DR InParanoid; Q9FI70; -.
DR OMA; CERWIEK; -.
DR OrthoDB; 973758at2759; -.
DR PhylomeDB; Q9FI70; -.
DR PRO; PR:Q9FI70; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FI70; baseline and differential.
DR Genevisible; Q9FI70; AT.
DR Gene3D; 2.120.10.80; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF117281; SSF117281; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..372
FT /note="F-box/kelch-repeat protein At5g49000"
FT /id="PRO_0000283277"
FT DOMAIN 19..65
FT /note="F-box"
FT REPEAT 131..177
FT /note="Kelch 1"
FT REPEAT 179..224
FT /note="Kelch 2"
FT REPEAT 226..271
FT /note="Kelch 3"
FT REPEAT 273..312
FT /note="Kelch 4"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 110..153
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:11910074"
FT /id="VSP_024432"
FT CONFLICT 206
FT /note="F -> L (in Ref. 3; BAC42576)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 372 AA; 42073 MW; D0BD69F949917FE3 CRC64;
MSSPERKRKK RSLEPSPEST PNPSLPDDLI VSILARVSRL YYPILSLVSK SSRTLVTSPE
LYKTRSFFNR TESCLYVCLD FPPDPNPRWF TLYRKPNQNI TEKTKNSSGF VLAPIPNHHS
HSSSIVAIGS NIYAIGGSIE NAPSSKVSIL DCRSHTWHEA PSMRMKRNYP AANVVDGKIY
VAGGLEEFDS SKWMEVFDIK TQTWEFVLSP LAERFIYRSL VIEGEIYIFG DKVVTYKPKE
DRWGGVGEHQ SMDLGLFFHS YCVIDNVLYC YRPGGIKWYE SEKRSWRKLR GLKGLSKLAS
SCVKLADYGG KMALLWDKYI PCSGNKSHSI SCAVVSLERC KNQGIRGKVE WFDDMLTVPS
SYNFVGALAA TL
