ID   FKBX_PSEFL              Reviewed;         150 AA.
AC   P21863;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Probable FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase;
DE            Short=PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Rotamase;
GN   Name=yaaD;
OS   Pseudomonas fluorescens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=294;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49323 / NCIMB 10586;
RX   PubMed=2121716; DOI=10.1128/jb.172.11.6512-6517.1990;
RA   Isaki L., Beers R., Wu H.C.;
RT   "Nucleotide sequence of the Pseudomonas fluorescens signal peptidase II
RT   gene (lsp) and flanking genes.";
RL   J. Bacteriol. 172:6512-6517(1990).
CC   -!- FUNCTION: PPIases accelerate the folding of proteins.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
CC   -!- SIMILARITY: Belongs to the FKBP-type PPIase family. {ECO:0000305}.
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DR   EMBL; M35366; AAA25885.1; -; Genomic_DNA.
DR   PIR; C37152; C37152.
DR   AlphaFoldDB; P21863; -.
DR   SMR; P21863; -.
DR   STRING; 690597.JH730966_gene5348; -.
DR   eggNOG; COG1047; Bacteria.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR001179; PPIase_FKBP_dom.
DR   Pfam; PF00254; FKBP_C; 1.
DR   PROSITE; PS50059; FKBP_PPIASE; 1.
PE   3: Inferred from homology;
KW   Isomerase; Rotamase.
FT   CHAIN           1..150
FT                   /note="Probable FKBP-type 16 kDa peptidyl-prolyl cis-trans
FT                   isomerase"
FT                   /id="PRO_0000075374"
FT   DOMAIN          14..88
FT                   /note="PPIase FKBP-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00277"
SQ   SEQUENCE   150 AA;  16373 MW;  A33926FE23BA0B6C CRC64;
     MTDQVLAEQR IGQNTEVTLH FALRLENGDT VDSTFDKAPA TFKVGDGNLL PGFEAALFGF
     KAGDKRTLQI LPENAFGQPN PQNVQIIPRS QFQNMDLSEG LLVIFNDAAN TELPGVVKAF
     DDAQVTIDFN HPLAGKTLTF DVEIIDVKAL