ID   FL2_TOBAC               Reviewed;         416 AA.
AC   Q40505;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Floricaula/leafy homolog 2;
DE   AltName: Full=NFL2;
GN   Name=FL2;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Samsun;
RX   PubMed=7756832; DOI=10.2307/3869998;
RA   Kelly A.J., Bonnlander M.B., Meeks-Wagner D.R.;
RT   "NFL, the tobacco homolog of FLORICAULA and LEAFY, is transcriptionally
RT   expressed in both vegetative and floral meristems.";
RL   Plant Cell 7:225-234(1995).
CC   -!- FUNCTION: Probable transcription factor that act to specify determinacy
CC       in the progenitor cells for both flowers and leaves.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in floral meristems and in indeterminate
CC       vegetative meristems.
CC   -!- SIMILARITY: Belongs to the FLO/LFY family. {ECO:0000305}.
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DR   EMBL; U16174; AAC48986.1; -; Genomic_DNA.
DR   EMBL; U15799; AAC48986.1; JOINED; Genomic_DNA.
DR   EMBL; U16173; AAC48986.1; JOINED; Genomic_DNA.
DR   PIR; T03243; T03243.
DR   RefSeq; XP_016449328.1; XM_016593842.1.
DR   AlphaFoldDB; Q40505; -.
DR   SMR; Q40505; -.
DR   STRING; 4097.Q40505; -.
DR   GeneID; 107774346; -.
DR   KEGG; nta:107774346; -.
DR   OMA; IFNTHPR; -.
DR   OrthoDB; 1031599at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.4180.10; -; 1.
DR   InterPro; IPR035209; FLO/LFY_C.
DR   InterPro; IPR002910; FLO_LFY.
DR   InterPro; IPR038276; Floricaula/leafy_C_sf.
DR   InterPro; IPR035079; LFY_SAM.
DR   PANTHER; PTHR36079; PTHR36079; 1.
DR   Pfam; PF17538; C_LFY_FLO; 1.
DR   Pfam; PF01698; SAM_LFY; 1.
PE   2: Evidence at transcript level;
KW   Activator; Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..416
FT                   /note="Floricaula/leafy homolog 2"
FT                   /id="PRO_0000129157"
FT   DNA_BIND        238..242
FT                   /evidence="ECO:0000250"
FT   DNA_BIND        307..314
FT                   /evidence="ECO:0000250"
FT   DNA_BIND        378..381
FT                   /evidence="ECO:0000250"
FT   REGION          154..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            285
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
FT   SITE            292
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
FT   SITE            296
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
FT   SITE            343
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   416 AA;  46127 MW;  73C255EE69C3B620 CRC64;
     MDPEAFSASL FKWDPRGAMP PPTRLLEAAV APPPPPPALP PPQPLSAAYS IKTRELGGLE
     ELFQAYGIRY YTAAKIAELG FTVNTLLDMK DEELDDMMNS LSQIFRWELL VGERYGIKAA
     IRAERRRLEE EELRRRGHLL SDGGTNALDA LSQEGLSEEP VQQQEREAVG SGGGGTTWEV
     VAAAGGGRMK QRRRKKVVAA GREKRGGASA EEDEETEEGQ EDDWNINDAS GGISERQREH
     PFIVTEPGEV ARGKKNGLDY LFHLYEQCRD FLIQVQNIAK ERGEKCPTKV TNQVFRYAKK
     AGASYINKPK MRHYVHCYAL HCLDEEASNA LRRAFKERGE NVGAWRQACY KPLVAIAARQ
     GWDIDTIFNA HPRLAIWYVP TKLRQLCHSE RSNAAAAAAS SSVSGGGGGG DHLPHF