FLA12_ARATH
ID FLA12_ARATH Reviewed; 249 AA.
AC Q8LEE9; Q94EG7; Q9FKJ8;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 2.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Fasciclin-like arabinogalactan protein 12;
DE Flags: Precursor;
GN Name=FLA12; OrderedLocusNames=At5g60490; ORFNames=MUF9.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=14645732; DOI=10.1104/pp.103.031237;
RA Johnson K.L., Jones B.J., Bacic A., Schultz C.J.;
RT "The fasciclin-like arabinogalactan proteins of Arabidopsis. A multigene
RT family of putative cell adhesion molecules.";
RL Plant Physiol. 133:1911-1925(2003).
CC -!- FUNCTION: May be a cell surface adhesion protein.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the fasciclin-like AGP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK95321.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AAN18099.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AB011483; BAB08232.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97336.1; -; Genomic_DNA.
DR EMBL; AF410335; AAK95321.1; ALT_FRAME; mRNA.
DR EMBL; BT000530; AAN18099.1; ALT_FRAME; mRNA.
DR EMBL; AY085457; AAM62683.1; -; mRNA.
DR RefSeq; NP_200857.1; NM_125442.3.
DR AlphaFoldDB; Q8LEE9; -.
DR SMR; Q8LEE9; -.
DR STRING; 3702.AT5G60490.1; -.
DR PaxDb; Q8LEE9; -.
DR PRIDE; Q8LEE9; -.
DR ProteomicsDB; 230624; -.
DR EnsemblPlants; AT5G60490.1; AT5G60490.1; AT5G60490.
DR GeneID; 836170; -.
DR Gramene; AT5G60490.1; AT5G60490.1; AT5G60490.
DR KEGG; ath:AT5G60490; -.
DR Araport; AT5G60490; -.
DR TAIR; locus:2175153; AT5G60490.
DR eggNOG; ENOG502QQ1S; Eukaryota.
DR HOGENOM; CLU_067693_1_0_1; -.
DR InParanoid; Q8LEE9; -.
DR OMA; KAADSEC; -.
DR OrthoDB; 1358354at2759; -.
DR PhylomeDB; Q8LEE9; -.
DR PRO; PR:Q8LEE9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8LEE9; baseline and differential.
DR Genevisible; Q8LEE9; AT.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0009834; P:plant-type secondary cell wall biogenesis; IMP:TAIR.
DR Gene3D; 2.30.180.10; -; 1.
DR InterPro; IPR036378; FAS1_dom_sf.
DR InterPro; IPR000782; FAS1_domain.
DR InterPro; IPR045003; FLA_A.
DR PANTHER; PTHR32077; PTHR32077; 1.
DR Pfam; PF02469; Fasciclin; 1.
DR SMART; SM00554; FAS1; 1.
DR SUPFAM; SSF82153; SSF82153; 1.
DR PROSITE; PS50213; FAS1; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW Proteoglycan; Reference proteome; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..220
FT /note="Fasciclin-like arabinogalactan protein 12"
FT /id="PRO_0000253871"
FT PROPEP 221..249
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000253872"
FT DOMAIN 37..181
FT /note="FAS1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
FT REGION 186..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 220
FT /note="GPI-anchor amidated aspartate"
FT /evidence="ECO:0000255"
FT CARBOHYD 39
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 71
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 143
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 152
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 159
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 16
FT /note="Missing (in Ref. 4; AAM62683)"
FT /evidence="ECO:0000305"
FT CONFLICT 22
FT /note="I -> T (in Ref. 4; AAM62683)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 249 AA; 26367 MW; B30CB3EED022EA9A CRC64;
MEHSLIILLF TVLLLLTTTP GILSQPSPAV APAPPGPTNV TKILEKAGQF TVFIRLLKST
GVANQLYGQL NNSDNGITIF APSDSSFTGL KAGTLNSLTD EQQVELIQFH VIPSYVSSSN
FQTISNPLRT QAGDSADGHF PLNVTTSGNT VNITSGVTNT TVSGNVYSDG QLAVYQVDKV
LLPQQVFDPR PPAPAPAPSV SKSKKKKDDS DSSSDDSPAD ASFALRNVGS VCDAVSFCVM
SVMLAWFYL
