ID   FLA16_ARATH             Reviewed;         445 AA.
AC   Q8RWC5; Q9SJ64;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Fasciclin-like arabinogalactan protein 16;
DE   Flags: Precursor;
GN   Name=FLA16; OrderedLocusNames=At2g35860; ORFNames=F11F19.23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=14645732; DOI=10.1104/pp.103.031237;
RA   Johnson K.L., Jones B.J., Bacic A., Schultz C.J.;
RT   "The fasciclin-like arabinogalactan proteins of Arabidopsis. A multigene
RT   family of putative cell adhesion molecules.";
RL   Plant Physiol. 133:1911-1925(2003).
CC   -!- FUNCTION: May be a cell surface adhesion protein.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the fasciclin-like AGP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD21471.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC007017; AAD21471.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC09172.1; -; Genomic_DNA.
DR   EMBL; AY093189; AAM13188.1; -; mRNA.
DR   EMBL; BT006590; AAP31934.1; -; mRNA.
DR   PIR; H84773; H84773.
DR   RefSeq; NP_850253.1; NM_179922.2.
DR   AlphaFoldDB; Q8RWC5; -.
DR   SMR; Q8RWC5; -.
DR   BioGRID; 3503; 1.
DR   STRING; 3702.AT2G35860.1; -.
DR   PaxDb; Q8RWC5; -.
DR   PRIDE; Q8RWC5; -.
DR   ProteomicsDB; 228935; -.
DR   EnsemblPlants; AT2G35860.1; AT2G35860.1; AT2G35860.
DR   GeneID; 818159; -.
DR   Gramene; AT2G35860.1; AT2G35860.1; AT2G35860.
DR   KEGG; ath:AT2G35860; -.
DR   Araport; AT2G35860; -.
DR   TAIR; locus:2039270; AT2G35860.
DR   eggNOG; KOG1437; Eukaryota.
DR   HOGENOM; CLU_047484_0_0_1; -.
DR   InParanoid; Q8RWC5; -.
DR   OMA; SHIVPER; -.
DR   OrthoDB; 984651at2759; -.
DR   PhylomeDB; Q8RWC5; -.
DR   PRO; PR:Q8RWC5; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8RWC5; baseline and differential.
DR   Genevisible; Q8RWC5; AT.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProt.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.30.180.10; -; 2.
DR   InterPro; IPR036378; FAS1_dom_sf.
DR   InterPro; IPR000782; FAS1_domain.
DR   InterPro; IPR044654; FLA15/16/17/18.
DR   PANTHER; PTHR32499; PTHR32499; 1.
DR   Pfam; PF02469; Fasciclin; 2.
DR   SMART; SM00554; FAS1; 2.
DR   SUPFAM; SSF82153; SSF82153; 2.
DR   PROSITE; PS50213; FAS1; 2.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Proteoglycan; Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..445
FT                   /note="Fasciclin-like arabinogalactan protein 16"
FT                   /id="PRO_0000253876"
FT   DOMAIN          35..173
FT                   /note="FAS1 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
FT   DOMAIN          257..400
FT                   /note="FAS1 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
FT   CARBOHYD        72
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        279
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   445 AA;  49100 MW;  D1F4C58E3A7C057C CRC64;
     MDSSYGATKF LLLLFLTTSI ATALPDNKPV PGQINSNSVL VALLDSHYTE LAELVEKALL
     LQTLEEAVGK HNITIFAPRN DALERNLDPL FKSFLLEPRN LKSLQSLLMF HILPKRITSP
     QWPSLSHHHR TLSNDHLHLT VDVNTLKVDS AEIIRPDDVI RPDGIIHGIE RLLIPRSVQE
     DFNRRRSLRS ISAVIPEGAP EVDPRTHRLK KPSPAVPAGA PPVLPIYDAM SPGPSLAPAP
     APGPGGPRGH FNGDAQVKDF IHTLLHYGGY NEMADILVNL TSLATEMGRL VSEGYVLTVL
     APNDEAMAKL TTDQLSEPGA PEQIMYYHII PEYQTEESMY NAVRRFGKVK YDSLRFPHKV
     LAQEADGSVK FGHGDGSAYL FDPDIYTDGR ISVQGIDGVL FPKEETPATE IKPAAPVVKK
     VSKSRRGKLM EVACRMMGSR FIPCQ