FLA18_ARATH
ID FLA18_ARATH Reviewed; 462 AA.
AC Q93W32; Q9SRM7;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Fasciclin-like arabinogalactan protein 18;
DE Flags: Precursor;
GN Name=FLA18; OrderedLocusNames=At3g11700; ORFNames=T19F11.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=14645732; DOI=10.1104/pp.103.031237;
RA Johnson K.L., Jones B.J., Bacic A., Schultz C.J.;
RT "The fasciclin-like arabinogalactan proteins of Arabidopsis. A multigene
RT family of putative cell adhesion molecules.";
RL Plant Physiol. 133:1911-1925(2003).
CC -!- FUNCTION: May be a cell surface adhesion protein.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the fasciclin-like AGP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF02137.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009918; AAF02137.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE75085.1; -; Genomic_DNA.
DR EMBL; AY056197; AAL07046.1; -; mRNA.
DR EMBL; AY058879; AAL24265.1; -; mRNA.
DR EMBL; AY133794; AAM91728.1; -; mRNA.
DR RefSeq; NP_566398.1; NM_112002.3.
DR AlphaFoldDB; Q93W32; -.
DR STRING; 3702.AT3G11700.1; -.
DR PaxDb; Q93W32; -.
DR PRIDE; Q93W32; -.
DR ProteomicsDB; 230430; -.
DR EnsemblPlants; AT3G11700.1; AT3G11700.1; AT3G11700.
DR GeneID; 820342; -.
DR Gramene; AT3G11700.1; AT3G11700.1; AT3G11700.
DR KEGG; ath:AT3G11700; -.
DR Araport; AT3G11700; -.
DR TAIR; locus:2098338; AT3G11700.
DR eggNOG; KOG1437; Eukaryota.
DR HOGENOM; CLU_047484_0_0_1; -.
DR InParanoid; Q93W32; -.
DR OMA; ESGHHNI; -.
DR OrthoDB; 984651at2759; -.
DR PhylomeDB; Q93W32; -.
DR PRO; PR:Q93W32; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q93W32; baseline and differential.
DR Genevisible; Q93W32; AT.
DR GO; GO:0031225; C:anchored component of membrane; IEA:UniProt.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0099503; C:secretory vesicle; HDA:TAIR.
DR Gene3D; 2.30.180.10; -; 2.
DR InterPro; IPR036378; FAS1_dom_sf.
DR InterPro; IPR000782; FAS1_domain.
DR InterPro; IPR044654; FLA15/16/17/18.
DR PANTHER; PTHR32499; PTHR32499; 1.
DR Pfam; PF02469; Fasciclin; 2.
DR SMART; SM00554; FAS1; 2.
DR SUPFAM; SSF82153; SSF82153; 2.
DR PROSITE; PS50213; FAS1; 2.
PE 2: Evidence at transcript level;
KW Glycoprotein; Proteoglycan; Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..462
FT /note="Fasciclin-like arabinogalactan protein 18"
FT /id="PRO_0000253878"
FT DOMAIN 40..185
FT /note="FAS1 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
FT DOMAIN 271..414
FT /note="FAS1 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
FT CARBOHYD 32
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 77
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 293
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 462 AA; 50792 MW; 5EE0BCDBF4CDD091 CRC64;
MDRCIYGCSV ITIFFSFFFL LNASALESGH HNITGSGQIN SNSVLVALLD SRYTELAELV
EKALLLQTLE DAVGRHNITI FAPRNEALER DLDPDFKRFL LQPGNLKSLQ TLLLSHIIPK
RVGSNQWPEE NSGRVKHVTL GHDQVLHLSK LKGTNGKRLV NSAVITRPDD LTRPDGLIHG
IERLLIPRSV QEDFNRRRNL RSISAVLPEG APEIDPRTNR LKKSATAVSV PAGSPPVLPI
ESAMAPGPSL APAPAPGPGG AHKHFNGDAQ VKDFIHTLLH YGGYNEMADI LVNLTSLATE
MGRLVSEGYV LTVLAPNDEA MGKLTTDQLS EPGAPEQIMY YHIIPEYQTE ESMYNSVRRF
GKVKYETLRF PHKVGAKEAD GSVKFGSGDR SAYLFDPDIY TDGRISVQGI DGVLFPEEKE
EETVKKPTGP VKKVVQPRRG KLLEVACSML GAIGKDSYLS RC
