FLA6_ARATH
ID FLA6_ARATH Reviewed; 247 AA.
AC Q9SIL7; Q9C5Q5;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Fasciclin-like arabinogalactan protein 6;
DE Flags: Precursor;
GN Name=FLA6; OrderedLocusNames=At2g20520; ORFNames=T13C7.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11554470; DOI=10.1023/a:1010683432529;
RA Gaspar Y., Johnson K.L., McKenna J.A., Bacic A., Schultz C.J.;
RT "The complex structures of arabinogalactan-proteins and the journey towards
RT understanding function.";
RL Plant Mol. Biol. 47:161-176(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=14645732; DOI=10.1104/pp.103.031237;
RA Johnson K.L., Jones B.J., Bacic A., Schultz C.J.;
RT "The fasciclin-like arabinogalactan proteins of Arabidopsis. A multigene
RT family of putative cell adhesion molecules.";
RL Plant Physiol. 133:1911-1925(2003).
CC -!- FUNCTION: May be a cell surface adhesion protein.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the fasciclin-like AGP family. {ECO:0000305}.
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DR EMBL; AF333972; AAK20859.1; -; mRNA.
DR EMBL; AC007109; AAD25652.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC07022.1; -; Genomic_DNA.
DR PIR; C84590; C84590.
DR RefSeq; NP_565475.1; NM_127612.3.
DR AlphaFoldDB; Q9SIL7; -.
DR SMR; Q9SIL7; -.
DR STRING; 3702.AT2G20520.1; -.
DR PaxDb; Q9SIL7; -.
DR PRIDE; Q9SIL7; -.
DR ProteomicsDB; 230841; -.
DR EnsemblPlants; AT2G20520.1; AT2G20520.1; AT2G20520.
DR GeneID; 816574; -.
DR Gramene; AT2G20520.1; AT2G20520.1; AT2G20520.
DR KEGG; ath:AT2G20520; -.
DR Araport; AT2G20520; -.
DR TAIR; locus:2054769; AT2G20520.
DR eggNOG; ENOG502R770; Eukaryota.
DR HOGENOM; CLU_067693_1_0_1; -.
DR InParanoid; Q9SIL7; -.
DR OMA; VQLILYH; -.
DR OrthoDB; 1402209at2759; -.
DR PhylomeDB; Q9SIL7; -.
DR PRO; PR:Q9SIL7; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIL7; baseline and differential.
DR Genevisible; Q9SIL7; AT.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0009834; P:plant-type secondary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 2.30.180.10; -; 1.
DR InterPro; IPR036378; FAS1_dom_sf.
DR InterPro; IPR000782; FAS1_domain.
DR InterPro; IPR045003; FLA_A.
DR PANTHER; PTHR32077; PTHR32077; 1.
DR Pfam; PF02469; Fasciclin; 1.
DR SMART; SM00554; FAS1; 1.
DR SUPFAM; SSF82153; SSF82153; 1.
DR PROSITE; PS50213; FAS1; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW Proteoglycan; Reference proteome; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..222
FT /note="Fasciclin-like arabinogalactan protein 6"
FT /id="PRO_0000253867"
FT PROPEP 223..247
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000253868"
FT DOMAIN 36..182
FT /note="FAS1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
FT REGION 192..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 222
FT /note="GPI-anchor amidated glycine"
FT /evidence="ECO:0000255"
FT CARBOHYD 38
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 57
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 70
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 142
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 153
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 247 AA; 26506 MW; 41F0AFD408AF62A9 CRC64;
MSSSLFSYVV LLIFLFTIPY IQSQPTAPAP TTEKSPINLT AILEAGHQFT TLIQLLNTTQ
VGFQVSVQLN SSDQGMTIFA PTDNAFNKLK PGTLNSLTYQ QQIQLMLYHI IPKYYSLSDL
LLASNPVRTQ ATGQDGGVFG LNFTGQAQSN QVNVSTGVVE TRINNALRQQ FPLAVYVVDS
VLLPEELFGT KTTPTGAPAP KSSTSSSDAD SPAADDEHKS AGSSVKRTSL GIVVSFALFC
CSVIYIA
