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FLAAL_BRAHW
ID   FLAAL_BRAHW             Reviewed;         216 AA.
AC   C0QWY9; C4MGG5;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Putative flagellar filament outer layer-like protein;
DE   AltName: Full=P-H42;
GN   Name=flaAL; OrderedLocusNames=BHWA1_02338;
OS   Brachyspira hyodysenteriae (strain ATCC 49526 / WA1).
OC   Bacteria; Spirochaetes; Brachyspirales; Brachyspiraceae; Brachyspira.
OX   NCBI_TaxID=565034;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND BIOTECHNOLOGY.
RX   PubMed=19179021; DOI=10.1016/j.vetmic.2008.12.018;
RA   Song Y., La T., Phillips N.D., Bellgard M.I., Hampson D.J.;
RT   "A reverse vaccinology approach to swine dysentery vaccine development.";
RL   Vet. Microbiol. 137:111-119(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49526 / WA1;
RX   PubMed=19262690; DOI=10.1371/journal.pone.0004641;
RA   Bellgard M.I., Wanchanthuek P., La T., Ryan K., Moolhuijzen P.,
RA   Albertyn Z., Shaban B., Motro Y., Dunn D.S., Schibeci D., Hunter A.,
RA   Barrero R., Phillips N.D., Hampson D.J.;
RT   "Genome sequence of the pathogenic intestinal spirochete Brachyspira
RT   hyodysenteriae reveals adaptations to its lifestyle in the porcine large
RT   intestine.";
RL   PLoS ONE 4:E4641-E4641(2009).
CC   -!- FUNCTION: Might be part of the flagella. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Periplasmic flagellum. Periplasm {ECO:0000305}.
CC   -!- BIOTECHNOLOGY: Has shown promise in a 4-component vaccine with
CC       BHWA1_00430 (AC C0QY54), SecA (AC C0QZS7) and BHWA1_00569 (AC C0QYX7).
CC       {ECO:0000269|PubMed:19179021}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACD74839.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; EU555169; ACD74839.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP001357; ACN84792.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0QWY9; -.
DR   STRING; 565034.BHWA1_02338; -.
DR   EnsemblBacteria; ACN84792; ACN84792; BHWA1_02338.
DR   KEGG; bhy:BHWA1_02338; -.
DR   eggNOG; ENOG5033RD4; Bacteria.
DR   HOGENOM; CLU_097187_0_0_12; -.
DR   OMA; FEFANTW; -.
DR   Proteomes; UP000001803; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR   InterPro; IPR006714; FlaA.
DR   Pfam; PF04620; FlaA; 1.
PE   1: Evidence at protein level;
KW   Bacterial flagellum; Periplasm.
FT   CHAIN           1..216
FT                   /note="Putative flagellar filament outer layer-like
FT                   protein"
FT                   /id="PRO_0000380706"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   216 AA;  24763 MW;  41F87E739BF1D824 CRC64;
     MFAQDAAQTG EQTTQNQGEN GNNFVTEAIT NYLIDDFEFA NTWQASMPRD YGVVSIIRRE
     GGPADVVAEG AENNKYILGA KVEYFRTGYP WFSVTPPRPV KIPGYTKELS VWVAGRNHNN
     RMSFYVYDVN GKPQAVGNEA LNFMGWKNIT VQIPANIRQE EFRGQVEQGI SFMGIHVKVD
     PRDSYGKYYI YFDQLMAKTD MYLETYREED DPLDTW
 
 
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