ID   FLAA_AQUAE              Reviewed;         518 AA.
AC   O67803;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Flagellin;
GN   Name=flaA; Synonyms=fliC; OrderedLocusNames=aq_1998;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC07764.1; -; Genomic_DNA.
DR   PIR; G70471; G70471.
DR   RefSeq; NP_214372.1; NC_000918.1.
DR   RefSeq; WP_010881308.1; NC_000918.1.
DR   PDB; 1ORY; X-ray; 2.45 A; B=464-518.
DR   PDB; 4IWB; X-ray; 1.75 A; A/B=478-518.
DR   PDBsum; 1ORY; -.
DR   PDBsum; 4IWB; -.
DR   AlphaFoldDB; O67803; -.
DR   SMR; O67803; -.
DR   IntAct; O67803; 1.
DR   STRING; 224324.aq_1998; -.
DR   EnsemblBacteria; AAC07764; AAC07764; aq_1998.
DR   KEGG; aae:aq_1998; -.
DR   PATRIC; fig|224324.8.peg.1545; -.
DR   eggNOG; COG1344; Bacteria.
DR   HOGENOM; CLU_011142_7_1_0; -.
DR   InParanoid; O67803; -.
DR   OMA; FEHTINN; -.
DR   OrthoDB; 636786at2; -.
DR   EvolutionaryTrace; O67803; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   1: Evidence at protein level;
KW   3D-structure; Bacterial flagellum; Reference proteome; Secreted.
FT   CHAIN           1..518
FT                   /note="Flagellin"
FT                   /id="PRO_0000182583"
FT   HELIX           478..496
FT                   /evidence="ECO:0007829|PDB:4IWB"
FT   HELIX           498..505
FT                   /evidence="ECO:0007829|PDB:4IWB"
FT   HELIX           510..518
FT                   /evidence="ECO:0007829|PDB:4IWB"
SQ   SEQUENCE   518 AA;  55177 MW;  B49C2503F89E3EA5 CRC64;
     MATRINYNYE AAVTYTSLKQ NERLMNKSLL RLSTGLRILS AADDASGLFI ADQLALVSAG
     LEQGNRNIQF GISALQIAEG GVSQIYDKLK TMYQKAVSAA NDINDPNARA ALQRDIENLR
     DAILKIAQDT EYNGIRLLNG SFNNVRIHYG ARSAQTLSVS ISSVLPQQLG GYVAEDSPAT
     ATDTNNVLTN IGTTNTNYSV ASGDSLAFTF TDGTSITFNS LNQLGYDFNN TGTYILDASA
     IVNTINNNPT LQGKGIRAYA ENVSEADLTF DTTNVNIDQG DEVTITFYSG GELVFTKTYT
     DTVTLDQFIA DINNQAGGKL IASKDPSGTK LVLSTPNGET ISVEVTVNDA DGDTVVSSIN
     LGALLQGAAG TVVNTSGATA SAVKVGTLIV MGSENFTVQG TGIAYFTAAT SGTFNSLNDV
     DVTTNKGAEI AQVLIQRAVR QVDTIRTQIG STINNLQAIY DAQAVAKDNT DNAESIIRNV
     DFAKEMTEFT KYQIRMQSGV AMLAQANALP QLVLQLLR