ID   FLAA_BORBU              Reviewed;         341 AA.
AC   P70856; O51612; Q44876;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Flagellar filament outer layer protein;
DE   AltName: Full=Sheath protein;
DE   Flags: Precursor;
GN   Name=flaA; OrderedLocusNames=BB_0668;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=212;
RX   PubMed=8990312; DOI=10.1128/jb.179.2.552-556.1997;
RA   Ge Y., Charon N.W.;
RT   "An unexpected flaA homolog is present and expressed in Borrelia
RT   burgdorferi.";
RL   J. Bacteriol. 179:552-556(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 276-341.
RC   STRAIN=212;
RX   PubMed=9765799; DOI=10.1016/s0923-2508(97)85239-4;
RA   Trueba G.A., Old I.G., Saint-Girons I., Johnson R.C.;
RT   "A cheA cheW operon in Borrelia burgdorferi, the agent of Lyme disease.";
RL   Res. Microbiol. 148:191-200(1997).
CC   -!- FUNCTION: Component of the outer layer of the flagella.
CC   -!- SUBUNIT: The flagellum consists of an outer layer composed of repeating
CC       units of FlaA around a core that contains several antigenically related
CC       polypeptides.
CC   -!- SUBCELLULAR LOCATION: Periplasmic flagellum. Periplasm.
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DR   EMBL; U62900; AAC44770.1; -; Genomic_DNA.
DR   EMBL; AE000783; AAC67025.2; -; Genomic_DNA.
DR   EMBL; X91907; CAA63001.1; -; Genomic_DNA.
DR   PIR; C70183; C70183.
DR   RefSeq; NP_212802.2; NC_001318.1.
DR   RefSeq; WP_002656539.1; NC_001318.1.
DR   AlphaFoldDB; P70856; -.
DR   STRING; 224326.BB_0668; -.
DR   PRIDE; P70856; -.
DR   EnsemblBacteria; AAC67025; AAC67025; BB_0668.
DR   GeneID; 56567478; -.
DR   KEGG; bbu:BB_0668; -.
DR   PATRIC; fig|224326.49.peg.1059; -.
DR   HOGENOM; CLU_793811_0_0_12; -.
DR   OMA; EDMSGME; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR   InterPro; IPR006714; FlaA.
DR   InterPro; IPR016369; FlaA_Spirochaetes.
DR   Pfam; PF04620; FlaA; 1.
DR   PIRSF; PIRSF002892; Flagellin_A; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..341
FT                   /note="Flagellar filament outer layer protein"
FT                   /id="PRO_0000009351"
FT   CONFLICT        254..255
FT                   /note="EQ -> VK (in Ref. 1; AAC44770)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        317..318
FT                   /note="MP -> IA (in Ref. 1 and 3)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   341 AA;  38441 MW;  60B1475E8ADF3451 CRC64;
     MKRKAKSILF FLLSTVLFAQ ETDGLAEGSK RAEPGELVLD FAELARDPSS TRLDLTNYVD
     YVYSGASGIV KPEDMVVDLG INNWSVLLTP SARLQAYVKN SVVAPAVVKS ESKRYAGDTI
     LGVRVLFPSY SQSSAMIMPP FKIPFYSGES GNQFLGKGLI DNIKTMKEIK VSVYSLGYEI
     DLEVLFEDMN GMEYAYSMGT LKFKGWADLI WSNPNYIPNI SSRIIKDDVP NYPLASSKMR
     FKAFRVSKSH SSKEQNFIFY VKDLRVLYDK LSVSIDSDID SESVFKVYET SGTESLRKLK
     AHETFKRVLK LREKISMPEG SFQNFVEKIE SEKPEESSPK N