ID   FLAA_HELFC              Reviewed;         513 AA.
AC   Q9XB38; E7A9B2;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Flagellin A;
GN   Name=flaA; OrderedLocusNames=Hfelis_04060;
OS   Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=936155;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49179 / NCTC 12436 / CS1;
RX   PubMed=10411751; DOI=10.1046/j.1365-2958.1999.01478.x;
RA   Josenhans C., Ferrero R.L., Labigne A., Suerbaum S.;
RT   "Cloning and allelic exchange mutagenesis of two flagellin genes of
RT   Helicobacter felis.";
RL   Mol. Microbiol. 33:350-362(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49179 / NCTC 12436 / CS1;
RA   Arnold A., Zigova Z., Lawley T., Falkow S., Bentley S., Aslett M.,
RA   Muller A.;
RT   "Comparative whole genome analysis of the carcinogenic bacterial pathogen
RT   Helicobacter felis.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella. Important for motility and
CC       virulence.
CC   -!- SUBUNIT: Heteromer of FlaA and FlaB. FlaB is located proximal to the
CC       hook while the remainder of the filament is composed of the predominant
CC       FlaA.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; Y11601; CAB46858.1; -; Genomic_DNA.
DR   EMBL; FQ670179; CBY82490.1; -; Genomic_DNA.
DR   RefSeq; WP_013468860.1; NC_014810.2.
DR   AlphaFoldDB; Q9XB38; -.
DR   SMR; Q9XB38; -.
DR   STRING; 936155.HFELIS_04060; -.
DR   EnsemblBacteria; CBY82490; CBY82490; HFELIS_04060.
DR   GeneID; 36134401; -.
DR   KEGG; hfe:HFELIS_04060; -.
DR   eggNOG; COG1344; Bacteria.
DR   HOGENOM; CLU_011142_7_1_7; -.
DR   OMA; MAERNAM; -.
DR   OrthoDB; 636786at2; -.
DR   Proteomes; UP000007934; Chromosome.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF07196; Flagellin_IN; 2.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Secreted; Virulence.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..513
FT                   /note="Flagellin A"
FT                   /id="PRO_0000182607"
SQ   SEQUENCE   513 AA;  53529 MW;  A48F724F272C256A CRC64;
     MAFQVNTNIN ALNAHAMGLV TQRELKESLE RLSSGLRINK AADDASGMTI ADSLRSQAKS
     LGQAIANTND GMGIIQIADK AMDEQIKILD TIKVKATQAA QDGQNTQSRK ALQADIVRLI
     QSLDNIGNTT SYNGQTLLSG AFSNKEFQVG AYSNETIKAS IGSATSDKIG QVKITTGKNI
     TASGEVALTF KQVDGVHDVS LESVKISTSA GTGLGVLAEV INKNSNATGV RATANVITTS
     DSAIKSGSLS SLTVNGIEIG NILGIKKNDS DGRLVAALNA VTAQTGVEAY TDSVGRLNLR
     SIDGRGINIK ANSTNVDGQA SALTTLNGGQ DITRGSTNFG RLSLVRQDAR DILVVSGANV
     SASAGYAAIG FAKGTTANTT VNLRDVLGEF NQAVRSASGA NYNKTLASEN LTLGSGVTTL
     RGAMVVMDIA ESAQKMLDKV RSDLGSVQNQ MVSTVNNITI TQVNVKAAES QIRDVDFAQE
     SANFSKNNIL AQSGSYAMSQ ANTVQQNILR LLT