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FLAA_HELPJ
ID   FLAA_HELPJ              Reviewed;         510 AA.
AC   P0A0S2; Q03843;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Flagellin A;
GN   Name=flaA; OrderedLocusNames=jhp_0548;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella. Important for motility and
CC       virulence (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heteromer of FlaA and FlaB. FlaB is located proximal to the
CC       hook while the remainder of the filament is composed of the predominant
CC       FlaA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Bacterial flagellum
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; AE001439; AAD06133.1; -; Genomic_DNA.
DR   PIR; A64595; A64595.
DR   RefSeq; WP_000885496.1; NZ_CP011330.1.
DR   AlphaFoldDB; P0A0S2; -.
DR   SMR; P0A0S2; -.
DR   STRING; 85963.jhp_0548; -.
DR   EnsemblBacteria; AAD06133; AAD06133; jhp_0548.
DR   GeneID; 66521826; -.
DR   KEGG; hpj:jhp_0548; -.
DR   PATRIC; fig|85963.30.peg.445; -.
DR   eggNOG; COG1344; Bacteria.
DR   OMA; MAERNAM; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF07196; Flagellin_IN; 2.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Secreted; Virulence.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..510
FT                   /note="Flagellin A"
FT                   /id="PRO_0000182610"
SQ   SEQUENCE   510 AA;  53284 MW;  E802CCB74474A65A CRC64;
     MAFQVNTNIN AMNAHVQSAL TQNALKTSLE RLSSGLRINK AADDASGMTV ADSLRSQASS
     LGQAIANTND GMGIIQVADK AMDEQLKILD TVKVKATQAA QDGQTTESRK AIQSDIVRLI
     QGLDNIGNTT TYNGQALLSG QFTNKEFQVG AYSNQSIKAS IGSTTSDKIG QVRIATGALI
     TASGDISLTF KQVDGVNDVT LESVKVSSSA GTGIGVLAEV INKNSNRTGV KAYASVITTS
     DVAVQSGSLS NLTLNGIHLG NIADIKKNDS DGRLVAAINA VTSETGVEAY TDQKGRLNLR
     SIDGRGIEIK TDSVSNGPSA LTMVNGGQDL TKGSTNYGRL SLTRLDAKSI NVVSASDSQH
     LGFTAIGFGE SQVAETTVNL RDVTGNFNAN VKSASGANYN AVIASGNQSL GSGVTTLRGA
     MVVIDIAESA MKMLDKVRSD LGSVQNQMIS TVNNISITQV NVKAAESQIR DVDFAEESAN
     FNKNNILAQS GSYAMSQANT VQQNILRLLT
 
 
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