ID   FLAA_VIBPA              Reviewed;         376 AA.
AC   Q56703;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Polar flagellin A;
GN   Name=flaA; OrderedLocusNames=VP2258;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BB22;
RX   PubMed=7883718; DOI=10.1128/jb.177.6.1595-1609.1995;
RA   McCarter L.L.;
RT   "Genetic and molecular characterization of the polar flagellum of Vibrio
RT   parahaemolyticus.";
RL   J. Bacteriol. 177:1595-1609(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella. FlaA is not essential for polar
CC       flagellar synthesis and swimming motility. Homomer of FlaA is able to
CC       form a functional filament.
CC   -!- SUBUNIT: Heteromer of multiple flagellin subunits including FlaA,
CC       FlaB/D, FlaC, FlaE and FlaF.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- MISCELLANEOUS: V.parahaemolyticus possesses two flagellar systems: a
CC       single polar flagellum propels the bacterium in liquid (swimming),
CC       while multiple lateral (peritrichous) flagella move the bacterium over
CC       surfaces (swarming). The polar flagellum is synthesized constitutively
CC       but lateral flagella are produced only under conditions in which the
CC       polar flagellum is not functional.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; AF069392; AAC27801.1; -; Genomic_DNA.
DR   EMBL; BA000031; BAC60521.1; -; Genomic_DNA.
DR   RefSeq; NP_798637.1; NC_004603.1.
DR   RefSeq; WP_005457770.1; NC_004603.1.
DR   AlphaFoldDB; Q56703; -.
DR   SMR; Q56703; -.
DR   STRING; 223926.28807251; -.
DR   EnsemblBacteria; BAC60521; BAC60521; BAC60521.
DR   GeneID; 1189771; -.
DR   KEGG; vpa:VP2258; -.
DR   PATRIC; fig|223926.6.peg.2161; -.
DR   eggNOG; COG1344; Bacteria.
DR   HOGENOM; CLU_011142_4_0_6; -.
DR   OMA; MAERNAM; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..376
FT                   /note="Polar flagellin A"
FT                   /id="PRO_0000182653"
FT   COILED          103..128
FT                   /evidence="ECO:0000255"
FT   COILED          310..338
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   376 AA;  39849 MW;  34AD3ABD19787C59 CRC64;
     MAINVNTNVS AMTAQRYLNH AAEGQQKSME RLSSGYKINS AKDDAAGLQI SNRLNAQSRG
     LDMAVKNAND GISIAQVAEG AMNESTNILQ RMRDLSLQSA NGSNSKAERV AIQEEVTALN
     DELNRIAETT SFGGNKLLNG TYGTQSFQIG ADSGEAVMLS MGSLRSDTSA MGGKSYSAEE
     GKDASWTVGD KTELKMSYTN KQGEEKELTI KAKQGDDIEQ LATYINGQSE DVKASVGEDG
     KLQVFASTQK VNGEVEFSGN LAGEIGFGDA KDVTVKDIDV TTVAGSQEAV AVIDGALKSV
     DSQRASLGAF QNRFNHAISN LDNINENVNA SNSRIKDTDY AKETTAMTKS QILQQASTSI
     LAQAKQSPSA ALSLLG