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FLAB_LEPIN
ID   FLAB_LEPIN              Reviewed;         283 AA.
AC   O51941;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2002, sequence version 2.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Flagellar filament 35 kDa core protein;
DE   AltName: Full=35 kDa antigen;
DE   AltName: Full=Flagellin class B;
GN   Name=flaB; Synonyms=flaB2; OrderedLocusNames=LA_2019;
OS   Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS   56601).
OC   Bacteria; Spirochaetes; Leptospirales; Leptospiraceae; Leptospira.
OX   NCBI_TaxID=189518;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-13.
RC   STRAIN=Serogroup Pomona;
RX   PubMed=9317049; DOI=10.1128/iai.65.10.4355-4359.1997;
RA   Lin M., Surujballi O., Nielsen K., Nadin-Davis S., Randall G.;
RT   "Identification of a 35-kilodalton serovar-cross-reactive flagellar
RT   protein, FlaB, from Leptospira interrogans by N-terminal sequencing, gene
RT   cloning, and sequence analysis.";
RL   Infect. Immun. 65:4355-4359(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=56601;
RX   PubMed=12712204; DOI=10.1038/nature01597;
RA   Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X.,
RA   Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X.,
RA   Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H., Yin H.-F., Zhang Y., Zhu G.-F.,
RA   Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y.,
RA   Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I.,
RA   Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P.;
RT   "Unique physiological and pathogenic features of Leptospira interrogans
RT   revealed by whole-genome sequencing.";
RL   Nature 422:888-893(2003).
CC   -!- FUNCTION: Component of the core of the flagella. {ECO:0000305}.
CC   -!- SUBUNIT: The flagellum consists of two outer layers around a core that
CC       contains several antigenically related polypeptides.
CC   -!- SUBCELLULAR LOCATION: Periplasmic flagellum. Periplasm.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; AF014114; AAB94024.1; -; Genomic_DNA.
DR   EMBL; AE010300; AAN49218.1; -; Genomic_DNA.
DR   RefSeq; NP_712200.1; NC_004342.2.
DR   RefSeq; WP_000586168.1; NC_004342.2.
DR   AlphaFoldDB; O51941; -.
DR   SMR; O51941; -.
DR   STRING; 189518.LA_2019; -.
DR   EnsemblBacteria; AAN49218; AAN49218; LA_2019.
DR   KEGG; lil:LA_2019; -.
DR   PATRIC; fig|189518.3.peg.2015; -.
DR   HOGENOM; CLU_011142_2_0_12; -.
DR   InParanoid; O51941; -.
DR   OMA; NGVASQH; -.
DR   Proteomes; UP000001408; Chromosome I.
DR   GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   1: Evidence at protein level;
KW   Bacterial flagellum; Direct protein sequencing; Periplasm;
KW   Reference proteome.
FT   CHAIN           1..283
FT                   /note="Flagellar filament 35 kDa core protein"
FT                   /id="PRO_0000182616"
FT   CONFLICT        56
FT                   /note="I -> V (in Ref. 1; AAB94024)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        268
FT                   /note="Q -> R (in Ref. 1; AAB94024)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        282
FT                   /note="Q -> H (in Ref. 1; AAB94024)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   283 AA;  31272 MW;  0C1ED44A7057F856 CRC64;
     MIINHNLSAV NAHRSLKFNE LAVDKTMKAL SSGMRINSAA DDASGLAVSE KLRTQINGLR
     QAERNTEDGM SFIQTAEGFL EQTSNIIQRI RVLAIQTSNG IYSNEDRQLV QVEVSALVDE
     VDRIASQAEF NKFKLFEGQF ARGSRVASMW FHMGPNQNQR ERFYIGTMTS KALKLVKADG
     RPIAISSPGE ANDVIGLADA ALTKIMKQRA DMGAYYNRLE YTAKGLMGAY ENMQASESRI
     RDADMAEEVV SLTTKQILVQ SGTAMLAQAN MKPNSVLKLL QQI
 
 
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