FLAB_VIBC3
ID FLAB_VIBC3 Reviewed; 376 AA.
AC A5F6C4; C3M2X4; O34223;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Flagellin B;
GN Name=flaB; OrderedLocusNames=VC0395_A1726, VC395_2256;
OS Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS O395).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=345073;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9440520; DOI=10.1128/jb.180.2.303-316.1998;
RA Klose K.E., Mekalanos J.J.;
RT "Differential regulation of multiple flagellins in Vibrio cholerae.";
RL J. Bacteriol. 180:303-316(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA Heidelberg J.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC the filaments of bacterial flagella. FlaB is not essential for
CC flagellar synthesis and motility.
CC -!- SUBUNIT: Heteromer of multiple flagellin subunits including FlaA, FlaB,
CC FlaC, FlaD and FlaE.
CC -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC -!- MISCELLANEOUS: V.cholerae is able to differentially regulate the
CC flagellins within the flagellum maybe to produce flagella which are
CC particularly suited for motility within a given environment.
CC -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF007122; AAC01557.1; -; Genomic_DNA.
DR EMBL; CP000627; ABQ21259.1; -; Genomic_DNA.
DR EMBL; CP001235; ACP10248.1; -; Genomic_DNA.
DR RefSeq; WP_000996996.1; NZ_JAACZH010000001.1.
DR AlphaFoldDB; A5F6C4; -.
DR SMR; A5F6C4; -.
DR STRING; 345073.VC395_2256; -.
DR EnsemblBacteria; ABQ21259; ABQ21259; VC0395_A1726.
DR GeneID; 57740761; -.
DR KEGG; vco:VC0395_A1726; -.
DR KEGG; vcr:VC395_2256; -.
DR PATRIC; fig|345073.21.peg.2180; -.
DR eggNOG; COG1344; Bacteria.
DR HOGENOM; CLU_011142_7_2_6; -.
DR OMA; MAERNAM; -.
DR Proteomes; UP000000249; Chromosome 2.
DR GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 6.10.10.10; -; 1.
DR InterPro; IPR001492; Flagellin.
DR InterPro; IPR046358; Flagellin_C.
DR InterPro; IPR042187; Flagellin_C_sub2.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR001029; Flagellin_N.
DR PANTHER; PTHR42792; PTHR42792; 1.
DR Pfam; PF00700; Flagellin_C; 1.
DR Pfam; PF07196; Flagellin_IN; 1.
DR Pfam; PF00669; Flagellin_N; 1.
DR PRINTS; PR00207; FLAGELLIN.
PE 3: Inferred from homology;
KW Bacterial flagellum; Coiled coil; Secreted.
FT CHAIN 1..376
FT /note="Flagellin B"
FT /id="PRO_0000321847"
FT COILED 103..129
FT /evidence="ECO:0000255"
SQ SEQUENCE 376 AA; 39517 MW; 4483E74394E2B2F9 CRC64;
MAINVNTNVS AMTAQRYLNG AADGMQKSME RLSSGYKINS ARDDAAGLQI SNRLTSQSRG
LDMAVKNAND GISIAQTAEG AMNETTNILQ RMRDLALQSS NGSNSSSERR AIQEEVSALN
DELNRIAETT SFGGNKLLNG SFGSKSFQIG ADSGEAVMLS MGSMRSDTQA MGGKSYRAQE
GKAADWRVGA ATDLTLSYTN KQGEAREVTI NAKQGDDLEE LATYINGQTE DVKASVGEDG
KLQLFASSQK VNGDVTIGGG LGGEIGFDAG RNVTVADVNV STVAGSQEAV SILDGALKAV
DSQRASLGAF QNRFGHAISN LDNVNENVNA SRSRIRDTDY ARETTAMTKA QILQQASTSV
LAQAKQSPSA ALSLLG
