FLAC_VIBC3
ID FLAC_VIBC3 Reviewed; 377 AA.
AC A5F671; C3M3E4; O34221;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Flagellin C;
GN Name=flaC; OrderedLocusNames=VC0395_A1779, VC395_2303;
OS Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS O395).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=345073;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9440520; DOI=10.1128/jb.180.2.303-316.1998;
RA Klose K.E., Mekalanos J.J.;
RT "Differential regulation of multiple flagellins in Vibrio cholerae.";
RL J. Bacteriol. 180:303-316(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA Heidelberg J.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC the filaments of bacterial flagella. FlaC is not essential for
CC flagellar synthesis and motility.
CC -!- SUBUNIT: Heteromer of multiple flagellin subunits including FlaA, FlaB,
CC FlaC, FlaD and FlaE.
CC -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC -!- MISCELLANEOUS: V.cholerae is able to differentially regulate the
CC flagellins within the flagellum maybe to produce flagella which are
CC particularly suited for motility within a given environment.
CC -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR EMBL; AF007121; AAC01553.1; -; Genomic_DNA.
DR EMBL; CP000627; ABQ21841.1; -; Genomic_DNA.
DR EMBL; CP001235; ACP10293.1; -; Genomic_DNA.
DR RefSeq; WP_000290380.1; NZ_JAACZH010000022.1.
DR AlphaFoldDB; A5F671; -.
DR SMR; A5F671; -.
DR STRING; 345073.VC395_2303; -.
DR EnsemblBacteria; ABQ21841; ABQ21841; VC0395_A1779.
DR KEGG; vco:VC0395_A1779; -.
DR KEGG; vcr:VC395_2303; -.
DR PATRIC; fig|345073.21.peg.2219; -.
DR eggNOG; COG1344; Bacteria.
DR HOGENOM; CLU_011142_4_0_6; -.
DR OMA; NGVASQH; -.
DR Proteomes; UP000000249; Chromosome 2.
DR GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 6.10.10.10; -; 1.
DR InterPro; IPR001492; Flagellin.
DR InterPro; IPR046358; Flagellin_C.
DR InterPro; IPR042187; Flagellin_C_sub2.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR001029; Flagellin_N.
DR PANTHER; PTHR42792; PTHR42792; 1.
DR Pfam; PF00700; Flagellin_C; 1.
DR Pfam; PF07196; Flagellin_IN; 1.
DR Pfam; PF00669; Flagellin_N; 1.
DR PRINTS; PR00207; FLAGELLIN.
PE 3: Inferred from homology;
KW Bacterial flagellum; Coiled coil; Secreted.
FT CHAIN 1..377
FT /note="Flagellin C"
FT /id="PRO_0000321848"
FT COILED 103..129
FT /evidence="ECO:0000255"
FT COILED 301..340
FT /evidence="ECO:0000255"
SQ SEQUENCE 377 AA; 39905 MW; 069DE4AC9C4B554B CRC64;
MAVNVNTNVS AMTAQRYLTS ATNAQQSSME RLSSGYKINS AKDDAAGLQI SNRLNVQSRG
LGVAVRNAND GISMAQTAEG AMKETTNILQ RMRDLSLQSA NGSNSKADRV AIQEEITALN
DELNRVAETT SFGGNKLLNG TFATKSFQIG ADNGEAVMLN IKDMRSDNAL MGGKTYQAAN
GKDKNWGVEA GKTDLTITLK DKREGDVTIS INAKEGDDIE ELATYINGQT DMIKASVDEE
GKLQLFTDNN RIDGAATFGG ALAGELGIGA AQDVTVDTLD VTTVGGAQES VAIVDAALKY
VDSHRAELGA FQNRFNHAIN NLDNINENVN ASKSRIKDTD FAKETTALTK AQILSQASSS
VLAQAKQAPN SALALLG