ID   FLAC_VIBCH              Reviewed;         377 AA.
AC   P0C6C5; O34221;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Flagellin C;
GN   Name=flaC; OrderedLocusNames=VC_2187;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella. FlaC is not essential for
CC       flagellar synthesis and motility (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heteromer of multiple flagellin subunits including FlaA, FlaB,
CC       FlaC, FlaD and FlaE. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Bacterial flagellum
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: V.cholerae is able to differentially regulate the
CC       flagellins within the flagellum maybe to produce flagella which are
CC       particularly suited for motility within a given environment.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; AE003852; AAF95332.1; -; Genomic_DNA.
DR   PIR; F82107; F82107.
DR   RefSeq; NP_231818.1; NC_002505.1.
DR   RefSeq; WP_000290380.1; NZ_LT906614.1.
DR   AlphaFoldDB; P0C6C5; -.
DR   SMR; P0C6C5; -.
DR   STRING; 243277.VC_2187; -.
DR   DNASU; 2613227; -.
DR   EnsemblBacteria; AAF95332; AAF95332; VC_2187.
DR   KEGG; vch:VC_2187; -.
DR   PATRIC; fig|243277.26.peg.2085; -.
DR   eggNOG; COG1344; Bacteria.
DR   HOGENOM; CLU_011142_4_0_6; -.
DR   OMA; NGVASQH; -.
DR   BioCyc; VCHO:VC2187-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..377
FT                   /note="Flagellin C"
FT                   /id="PRO_0000182650"
FT   COILED          103..129
FT                   /evidence="ECO:0000255"
FT   COILED          301..340
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   377 AA;  39905 MW;  069DE4AC9C4B554B CRC64;
     MAVNVNTNVS AMTAQRYLTS ATNAQQSSME RLSSGYKINS AKDDAAGLQI SNRLNVQSRG
     LGVAVRNAND GISMAQTAEG AMKETTNILQ RMRDLSLQSA NGSNSKADRV AIQEEITALN
     DELNRVAETT SFGGNKLLNG TFATKSFQIG ADNGEAVMLN IKDMRSDNAL MGGKTYQAAN
     GKDKNWGVEA GKTDLTITLK DKREGDVTIS INAKEGDDIE ELATYINGQT DMIKASVDEE
     GKLQLFTDNN RIDGAATFGG ALAGELGIGA AQDVTVDTLD VTTVGGAQES VAIVDAALKY
     VDSHRAELGA FQNRFNHAIN NLDNINENVN ASKSRIKDTD FAKETTALTK AQILSQASSS
     VLAQAKQAPN SALALLG