ID   FLAE_VIBPA              Reviewed;         374 AA.
AC   Q9ZBA2;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   11-APR-2003, sequence version 2.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Polar flagellin E;
GN   Name=flaE; OrderedLocusNames=VP0791;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BB22;
RX   PubMed=10850984; DOI=10.1128/jb.182.13.3693-3704.2000;
RA   Kim Y.-K., McCarter L.L.;
RT   "Analysis of the polar flagellar gene system of Vibrio parahaemolyticus.";
RL   J. Bacteriol. 182:3693-3704(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella.
CC   -!- SUBUNIT: Heteromer of multiple flagellin subunits including FlaA,
CC       FlaB/D, FlaC, FlaE and FlaF.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- MISCELLANEOUS: V.parahaemolyticus possesses two flagellar systems: a
CC       single polar flagellum propels the bacterium in liquid (swimming),
CC       while multiple lateral (peritrichous) flagella move the bacterium over
CC       surfaces (swarming). The polar flagellum is synthesized constitutively
CC       but lateral flagella are produced only under conditions in which the
CC       polar flagellum is not functional.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; U12817; AAD10273.1; -; Genomic_DNA.
DR   EMBL; BA000031; BAC59054.1; -; Genomic_DNA.
DR   RefSeq; NP_797170.1; NC_004603.1.
DR   RefSeq; WP_005482232.1; NC_004603.1.
DR   AlphaFoldDB; Q9ZBA2; -.
DR   SMR; Q9ZBA2; -.
DR   STRING; 223926.28805777; -.
DR   PRIDE; Q9ZBA2; -.
DR   EnsemblBacteria; BAC59054; BAC59054; BAC59054.
DR   GeneID; 1188288; -.
DR   KEGG; vpa:VP0791; -.
DR   PATRIC; fig|223926.6.peg.754; -.
DR   eggNOG; COG1344; Bacteria.
DR   HOGENOM; CLU_011142_4_0_6; -.
DR   OMA; HIPEMGG; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..374
FT                   /note="Polar flagellin E"
FT                   /id="PRO_0000182656"
FT   COILED          102..126
FT                   /evidence="ECO:0000255"
FT   CONFLICT        109
FT                   /note="K -> T (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        158
FT                   /note="A -> T (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        203
FT                   /note="A -> T (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        206..207
FT                   /note="KV -> EA (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        215
FT                   /note="N -> S (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        253
FT                   /note="I -> V (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        282
FT                   /note="G -> R (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        289
FT                   /note="G -> S (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        327
FT                   /note="S -> L (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        344
FT                   /note="V -> E (in Ref. 1; AAD10273)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   374 AA;  40689 MW;  17AE9B153DC06419 CRC64;
     MVSLNTNVAA MMTQRHLSQA ADQNVESQRN LSSGYRINSA SDDAAGLQIS NTLHVQTRGI
     DVALRNAHDA YSVAQTAEGA LHESSDILQR LRSLGLQAAN GSHEQDDRKS LQQEVIALQD
     ELDRVAITTT FADKNLFNGS YGSQSFHIGA NANSISLALR NMRTHIPEMG GQHYLGDSLD
     KDWRVTRDNQ QFAFEYQDNE GQAQSKVLTL KVGDNLEEVA TYINAQQSVV DASVTQDHQL
     QFFTSTLNAP EGITWKGNFA DEMDIGSGEL VTVDDLDMST VGGAQLAIGV VDAAIKYVDS
     HRSEIGGFQN RVSGTIDNLN TINRSVSESK GRIRDTDFAR ESTVMVRSQV LQDATTALLA
     QAKQRPSSAL GLLS