ID   FLAV_AQUAE              Reviewed;         185 AA.
AC   O67866;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Flavodoxin;
GN   Name=fldA; Synonyms=floX; OrderedLocusNames=aq_2096;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Low-potential electron donor to a number of redox enzymes.
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the flavodoxin family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC07825.1; -; Genomic_DNA.
DR   PIR; F70479; F70479.
DR   RefSeq; NP_214435.1; NC_000918.1.
DR   RefSeq; WP_010881371.1; NC_000918.1.
DR   PDB; 2ARK; X-ray; 2.40 A; A/B/C/D/E/F=1-185.
DR   PDBsum; 2ARK; -.
DR   AlphaFoldDB; O67866; -.
DR   SMR; O67866; -.
DR   STRING; 224324.aq_2096; -.
DR   EnsemblBacteria; AAC07825; AAC07825; aq_2096.
DR   KEGG; aae:aq_2096; -.
DR   eggNOG; COG0655; Bacteria.
DR   HOGENOM; CLU_051402_2_0_0; -.
DR   InParanoid; O67866; -.
DR   OMA; CTTATVH; -.
DR   OrthoDB; 796211at2; -.
DR   EvolutionaryTrace; O67866; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   Gene3D; 3.40.50.360; -; 1.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR001226; Flavodoxin_CS.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   SUPFAM; SSF52218; SSF52218; 1.
DR   PROSITE; PS00201; FLAVODOXIN; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Electron transport; Flavoprotein; FMN; Reference proteome;
KW   Transport.
FT   CHAIN           1..185
FT                   /note="Flavodoxin"
FT                   /id="PRO_0000171602"
FT   DOMAIN          4..159
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00088"
FT   STRAND          2..8
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   STRAND          11..13
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           14..27
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   STRAND          32..38
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   TURN            39..41
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           44..49
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   STRAND          51..58
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           66..74
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           76..78
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   TURN            79..81
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   STRAND          87..97
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           101..114
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   STRAND          122..127
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   STRAND          130..141
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           145..165
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           172..178
FT                   /evidence="ECO:0007829|PDB:2ARK"
FT   HELIX           180..182
FT                   /evidence="ECO:0007829|PDB:2ARK"
SQ   SEQUENCE   185 AA;  20444 MW;  7C138666D5B89281 CRC64;
     MGKVLVIYDT RTGNTKKMAE LVAEGARSLE GTEVRLKHVD EATKEDVLWA DGLAVGSPTN
     MGLVSWKMKR FFDDVLGDLW GEIDGKIACA FSSSGGWGGG NEVACMSILT MLMNFGFLVF
     GVTDYVGKKF TLHYGAVVAG EPRSEEEKEA CRRLGRRLAE WVAIFVDGRK ELLEKIRKDP
     ARFVD