ID   FLAV_HELPY              Reviewed;         164 AA.
AC   O25776;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 124.
DE   RecName: Full=Flavodoxin;
GN   Name=fldA; OrderedLocusNames=HP_1161;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Low-potential electron donor to a number of redox enzymes.
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the flavodoxin family. {ECO:0000305}.
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DR   EMBL; AE000511; AAD08207.1; -; Genomic_DNA.
DR   PIR; A64665; A64665.
DR   RefSeq; NP_207952.1; NC_000915.1.
DR   RefSeq; WP_000516078.1; NC_018939.1.
DR   PDB; 2BMV; X-ray; 2.11 A; A=1-164.
DR   PDB; 2W5U; X-ray; 2.62 A; A/B=1-164.
DR   PDBsum; 2BMV; -.
DR   PDBsum; 2W5U; -.
DR   AlphaFoldDB; O25776; -.
DR   SMR; O25776; -.
DR   IntAct; O25776; 1.
DR   STRING; 85962.C694_05995; -.
DR   ChEMBL; CHEMBL4523947; -.
DR   PaxDb; O25776; -.
DR   EnsemblBacteria; AAD08207; AAD08207; HP_1161.
DR   KEGG; hpy:HP_1161; -.
DR   PATRIC; fig|85962.47.peg.1245; -.
DR   eggNOG; COG0716; Bacteria.
DR   OMA; ICGIPTW; -.
DR   PhylomeDB; O25776; -.
DR   EvolutionaryTrace; O25776; -.
DR   PRO; PR:O25776; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   Gene3D; 3.40.50.360; -; 1.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR010086; Flavodoxin_lc.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   PIRSF; PIRSF038996; FldA; 1.
DR   SUPFAM; SSF52218; SSF52218; 1.
DR   TIGRFAMs; TIGR01752; flav_long; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Electron transport; Flavoprotein; FMN; Reference proteome;
KW   Transport.
FT   CHAIN           1..164
FT                   /note="Flavodoxin"
FT                   /id="PRO_0000171634"
FT   DOMAIN          4..160
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00088"
FT   STRAND          4..8
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   STRAND          11..13
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           14..26
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   STRAND          28..33
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           34..36
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           39..42
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   STRAND          46..55
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   TURN            56..58
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           62..68
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           74..77
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   STRAND          79..86
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   TURN            89..91
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   TURN            96..98
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           99..107
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   STRAND          110..112
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   STRAND          116..118
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   STRAND          133..139
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   TURN            141..143
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           145..147
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   HELIX           148..159
FT                   /evidence="ECO:0007829|PDB:2BMV"
FT   TURN            160..162
FT                   /evidence="ECO:0007829|PDB:2BMV"
SQ   SEQUENCE   164 AA;  17492 MW;  EBAD44D97964608C CRC64;
     MGKIGIFFGT DSGNAEAIAE KISKAIGNAE VVDVAKASKE QFNSFTKVIL VAPTAGAGDL
     QTDWEDFLGT LEASDFATKT IGLVGLGDQD TYSETFAEGI FHIYEKAKAG KVVGQTPTDG
     YHFEASKAVE GGKFVGLVID EDNQDDLTDE RISKWVEQVK GSFA