ID   FLAV_KLEPN              Reviewed;         176 AA.
AC   O07026;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 2.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Flavodoxin;
GN   Name=fldA;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RC   STRAIN=ATCC 13883 / DSM 30104 / JCM 1662 / NBRC 14940 / NCIMB 13281 / NCTC
RC   9633;
RX   PubMed=9272865; DOI=10.1016/s0378-1119(97)00168-6;
RA   Achenbach L.A., Genova E.G.;
RT   "Transcriptional regulation of a second flavodoxin gene from Klebsiella
RT   pneumoniae.";
RL   Gene 194:235-240(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 135-176.
RC   STRAIN=ATCC 13883 / DSM 30104 / JCM 1662 / NBRC 14940 / NCIMB 13281 / NCTC
RC   9633;
RX   PubMed=9055816; DOI=10.1016/s0378-1119(96)00642-7;
RA   Achenbach L.A., Yang W.;
RT   "The fur gene from Klebsiella pneumoniae: characterization, genomic
RT   organization and phylogenetic analysis.";
RL   Gene 185:201-207(1997).
CC   -!- FUNCTION: Low-potential electron donor to a number of redox enzymes.
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250};
CC   -!- INDUCTION: By low iron conditions and by heat shock. Iron regulation is
CC       mediated through the fur protein. {ECO:0000269|PubMed:9272865}.
CC   -!- SIMILARITY: Belongs to the flavodoxin family. {ECO:0000305}.
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DR   EMBL; U67169; AAB65080.1; -; Genomic_DNA.
DR   EMBL; L23871; AAB51076.1; -; Genomic_DNA.
DR   RefSeq; WP_002894765.1; NZ_WYAL01000003.1.
DR   AlphaFoldDB; O07026; -.
DR   SMR; O07026; -.
DR   GeneID; 61331906; -.
DR   GeneID; 64296429; -.
DR   OMA; ICGIPTW; -.
DR   OrthoDB; 1961680at2; -.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   Gene3D; 3.40.50.360; -; 1.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR001226; Flavodoxin_CS.
DR   InterPro; IPR010086; Flavodoxin_lc.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   PIRSF; PIRSF038996; FldA; 1.
DR   SUPFAM; SSF52218; SSF52218; 1.
DR   TIGRFAMs; TIGR01752; flav_long; 1.
DR   PROSITE; PS00201; FLAVODOXIN; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Electron transport; Flavoprotein; FMN; Transport.
FT   CHAIN           1..176
FT                   /note="Flavodoxin"
FT                   /id="PRO_0000171636"
FT   DOMAIN          4..165
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00088"
SQ   SEQUENCE   176 AA;  19765 MW;  C40E5F80287D3636 CRC64;
     MAIIGIFFGS DTGNTENIAK MIQKQLGKDV ADVHDIAKSS KEDLEAHDIL LLGIPTWYYG
     EAQCDWDDFF PTLEEIDFNG KLVALFGCGD QEDYAEYFCD ALGTIRDIIE PRGATIVGHW
     PTAGYHFEAS KGLADDDHFV GLAIDEDRQP ELTNERVEKW VKQVAEELHL EEIKNA