ID   FLAV_SALTY              Reviewed;         176 AA.
AC   Q8ZQX1;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Flavodoxin 1;
GN   Name=fldA; OrderedLocusNames=STM0694;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [2]
RP   FUNCTION AS A COBALT REDUCTASE.
RX   PubMed=11408479; DOI=10.1074/jbc.m102510200;
RA   Fonseca M.V., Escalante-Semerena J.C.;
RT   "An in vitro reducing system for the enzymic conversion of cobalamin to
RT   adenosylcobalamin.";
RL   J. Biol. Chem. 276:32101-32108(2001).
CC   -!- FUNCTION: Low-potential electron donor to a number of redox enzymes
CC       (Potential). Involved in the reactivation of inactive cob(II)alamin in
CC       methionine synthase. {ECO:0000269|PubMed:11408479, ECO:0000305}.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the flavodoxin family. {ECO:0000305}.
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DR   EMBL; AE006468; AAL19638.1; -; Genomic_DNA.
DR   RefSeq; NP_459679.1; NC_003197.2.
DR   RefSeq; WP_001018621.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZQX1; -.
DR   BMRB; Q8ZQX1; -.
DR   SMR; Q8ZQX1; -.
DR   STRING; 99287.STM0694; -.
DR   PaxDb; Q8ZQX1; -.
DR   EnsemblBacteria; AAL19638; AAL19638; STM0694.
DR   GeneID; 1252214; -.
DR   GeneID; 66755149; -.
DR   KEGG; stm:STM0694; -.
DR   PATRIC; fig|99287.12.peg.725; -.
DR   HOGENOM; CLU_051402_1_1_6; -.
DR   PhylomeDB; Q8ZQX1; -.
DR   BioCyc; MetaCyc:MON-13232; -.
DR   BioCyc; SENT99287:STM0694-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   Gene3D; 3.40.50.360; -; 1.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR001226; Flavodoxin_CS.
DR   InterPro; IPR010086; Flavodoxin_lc.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   PIRSF; PIRSF038996; FldA; 1.
DR   SUPFAM; SSF52218; SSF52218; 1.
DR   TIGRFAMs; TIGR01752; flav_long; 1.
DR   PROSITE; PS00201; FLAVODOXIN; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   1: Evidence at protein level;
KW   Electron transport; Flavoprotein; FMN; Reference proteome; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..176
FT                   /note="Flavodoxin 1"
FT                   /id="PRO_0000171625"
FT   DOMAIN          4..165
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00088"
SQ   SEQUENCE   176 AA;  19637 MW;  8FE6DD30921955BD CRC64;
     MAITGIFFGS DTGNTENIAK MIQKQLGKDV ADVHDIAKSS KEDLEGYDIL LLGIPTWYYG
     EAQCDWDDFF PTLEEIDFNG KLVALFGCGD QEDYAEYFCD ALGTIRDIIE PRGATIVGHW
     PTAGYHFEAS KGLADDDHFV GLAIDEDRQP ELTAERVEKW VKQVSAELHL DDILNA