ID   FLAV_SHIFL              Reviewed;         176 AA.
AC   Q83S80;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Flavodoxin 1;
GN   Name=fldA; OrderedLocusNames=SF0609, S0620;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Low-potential electron donor to a number of redox enzymes.
CC       {ECO:0000305}.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the flavodoxin family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN42247.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP16118.1; -; Genomic_DNA.
DR   RefSeq; NP_706540.2; NC_004337.2.
DR   AlphaFoldDB; Q83S80; -.
DR   SMR; Q83S80; -.
DR   STRING; 198214.SF0609; -.
DR   EnsemblBacteria; AAN42247; AAN42247; SF0609.
DR   EnsemblBacteria; AAP16118; AAP16118; S0620.
DR   GeneID; 1026090; -.
DR   KEGG; sfl:SF0609; -.
DR   KEGG; sfx:S0620; -.
DR   PATRIC; fig|198214.7.peg.710; -.
DR   HOGENOM; CLU_051402_1_1_6; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   Gene3D; 3.40.50.360; -; 1.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR001226; Flavodoxin_CS.
DR   InterPro; IPR010086; Flavodoxin_lc.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   PIRSF; PIRSF038996; FldA; 1.
DR   SUPFAM; SSF52218; SSF52218; 1.
DR   TIGRFAMs; TIGR01752; flav_long; 1.
DR   PROSITE; PS00201; FLAVODOXIN; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   3: Inferred from homology;
KW   Electron transport; Flavoprotein; FMN; Reference proteome; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..176
FT                   /note="Flavodoxin 1"
FT                   /id="PRO_0000171642"
FT   DOMAIN          4..165
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00088"
FT   CONFLICT        4
FT                   /note="H -> T (in Ref. 2; AAP16118)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        117..119
FT                   /note="DAD -> VGH (in Ref. 2; AAP16118)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        128
FT                   /note="Q -> E (in Ref. 2; AAP16118)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        149
FT                   /note="H -> Q (in Ref. 2; AAP16118)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        155
FT                   /note="D -> E (in Ref. 2; AAP16118)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   176 AA;  19775 MW;  AF175E20CEA6ADBD CRC64;
     MAIHGIFFGS DTGNTENIAK MIQKQLGKDV ADVHDIAKSS KEDLEAYDIL LLGIPTWYYG
     EAQCDWDDFF PTLEEIDFNG KLVALFGCGD QEDYAEYFCD ALGTIRDIIE PRGATIDADW
     PTAGYHFQAS KGLADDDHFV GLAIDEDRHP ELTADRVEKW VKQISEELHL DEILNA