FLAW_ECOLI
ID FLAW_ECOLI Reviewed; 173 AA.
AC P0ABY4; P41050; Q2M9U6;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Flavodoxin 2;
GN Name=fldB; OrderedLocusNames=b2895, JW2863;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RA Hayes F.;
RT "Putative second gene (fldB) for flavodoxin in Escherichia coli.";
RL Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Low-potential electron donor to a number of redox enzymes.
CC {ECO:0000305}.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC -!- SIMILARITY: Belongs to the flavodoxin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z48060; CAA88140.1; -; Genomic_DNA.
DR EMBL; U28375; AAA83076.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75933.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76960.1; -; Genomic_DNA.
DR PIR; G65073; G65073.
DR RefSeq; NP_417371.1; NC_000913.3.
DR RefSeq; WP_001055874.1; NZ_STEB01000001.1.
DR PDB; 2MT9; NMR; -; A=1-173.
DR PDB; 2MTB; NMR; -; A=1-173.
DR PDBsum; 2MT9; -.
DR PDBsum; 2MTB; -.
DR AlphaFoldDB; P0ABY4; -.
DR SMR; P0ABY4; -.
DR BioGRID; 4262340; 10.
DR IntAct; P0ABY4; 8.
DR STRING; 511145.b2895; -.
DR jPOST; P0ABY4; -.
DR PaxDb; P0ABY4; -.
DR PRIDE; P0ABY4; -.
DR EnsemblBacteria; AAC75933; AAC75933; b2895.
DR EnsemblBacteria; BAE76960; BAE76960; BAE76960.
DR GeneID; 67415220; -.
DR GeneID; 947361; -.
DR KEGG; ecj:JW2863; -.
DR KEGG; eco:b2895; -.
DR PATRIC; fig|1411691.4.peg.3838; -.
DR EchoBASE; EB2559; -.
DR eggNOG; COG0716; Bacteria.
DR HOGENOM; CLU_051402_1_0_6; -.
DR InParanoid; P0ABY4; -.
DR OMA; ILGISTW; -.
DR PhylomeDB; P0ABY4; -.
DR BioCyc; EcoCyc:FLAVODOXIN2-MON; -.
DR BioCyc; MetaCyc:FLAVODOXIN2-MON; -.
DR PRO; PR:P0ABY4; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0010181; F:FMN binding; IDA:EcoCyc.
DR Gene3D; 3.40.50.360; -; 1.
DR InterPro; IPR008254; Flavodoxin/NO_synth.
DR InterPro; IPR001226; Flavodoxin_CS.
DR InterPro; IPR010086; Flavodoxin_lc.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR Pfam; PF00258; Flavodoxin_1; 1.
DR PIRSF; PIRSF038996; FldA; 1.
DR SUPFAM; SSF52218; SSF52218; 1.
DR TIGRFAMs; TIGR01752; flav_long; 1.
DR PROSITE; PS00201; FLAVODOXIN; 1.
DR PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Electron transport; Flavoprotein; FMN; Reference proteome;
KW Transport.
FT CHAIN 1..173
FT /note="Flavodoxin 2"
FT /id="PRO_0000171626"
FT DOMAIN 3..165
FT /note="Flavodoxin-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00088"
FT CONFLICT 115
FT /note="F -> C (in Ref. 1; CAA88140)"
FT /evidence="ECO:0000305"
FT STRAND 3..7
FT /evidence="ECO:0007829|PDB:2MT9"
FT STRAND 10..12
FT /evidence="ECO:0007829|PDB:2MT9"
FT HELIX 13..25
FT /evidence="ECO:0007829|PDB:2MT9"
FT TURN 27..29
FT /evidence="ECO:0007829|PDB:2MT9"
FT STRAND 30..34
FT /evidence="ECO:0007829|PDB:2MT9"
FT TURN 35..37
FT /evidence="ECO:0007829|PDB:2MT9"
FT HELIX 40..44
FT /evidence="ECO:0007829|PDB:2MT9"
FT STRAND 46..56
FT /evidence="ECO:0007829|PDB:2MT9"
FT TURN 57..59
FT /evidence="ECO:0007829|PDB:2MT9"
FT HELIX 63..68
FT /evidence="ECO:0007829|PDB:2MT9"
FT HELIX 71..74
FT /evidence="ECO:0007829|PDB:2MT9"
FT STRAND 81..88
FT /evidence="ECO:0007829|PDB:2MT9"
FT TURN 90..93
FT /evidence="ECO:0007829|PDB:2MT9"
FT TURN 95..98
FT /evidence="ECO:0007829|PDB:2MT9"
FT HELIX 99..110
FT /evidence="ECO:0007829|PDB:2MT9"
FT STRAND 114..116
FT /evidence="ECO:0007829|PDB:2MT9"
FT STRAND 129..133
FT /evidence="ECO:0007829|PDB:2MT9"
FT TURN 134..137
FT /evidence="ECO:0007829|PDB:2MT9"
FT STRAND 138..148
FT /evidence="ECO:0007829|PDB:2MT9"
FT HELIX 149..151
FT /evidence="ECO:0007829|PDB:2MT9"
FT HELIX 153..171
FT /evidence="ECO:0007829|PDB:2MT9"
SQ SEQUENCE 173 AA; 19700 MW; 89338715D106A68C CRC64;
MNMGLFYGSS TCYTEMAAEK IRDIIGPELV TLHNLKDDSP KLMEQYDVLI LGIPTWDFGE
IQEDWEAVWD QLDDLNLEGK IVALYGLGDQ LGYGEWFLDA LGMLHDKLST KGVKFVGYWP
TEGYEFTSPK PVIADGQLFV GLALDETNQY DLSDERIQSW CEQILNEMAE HYA
