ID   FLBT_CAUVC              Reviewed;         141 AA.
AC   P21297;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Flagellum biosynthesis repressor protein FlbT;
GN   Name=flbT; OrderedLocusNames=CC_1458;
OS   Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   PubMed=1699845; DOI=10.1016/0378-1119(90)90130-j;
RA   Schoenlein P.V., Gallman L.S., Winkler M.E., Ely B.;
RT   "Nucleotide sequence of the Caulobacter crescentus flaF and flbT genes and
RT   an analysis of codon usage in organisms with G + C-rich genomes.";
RL   Gene 93:17-25(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA   Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA   Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA   Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA   Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
RN   [3]
RP   FUNCTION.
RX   PubMed=11029689; DOI=10.1046/j.1365-2958.2000.02108.x;
RA   Anderson P.E., Gober J.W.;
RT   "FlbT, the post-transcriptional regulator of flagellin synthesis in
RT   Caulobacter crescentus, interacts with the 5' untranslated region of
RT   flagellin mRNA.";
RL   Mol. Microbiol. 38:41-52(2000).
CC   -!- FUNCTION: Has a post-transcriptional repressor function in flagellum
CC       biogenesis. Associates with the 5'-UTR of fljK (25 kDa flagellin) mRNA
CC       and promotes its degradation. {ECO:0000269|PubMed:11029689}.
CC   -!- SIMILARITY: Belongs to the FlbT family. {ECO:0000305}.
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DR   EMBL; X15134; CAA33230.1; -; Genomic_DNA.
DR   EMBL; AE005673; AAK23439.1; -; Genomic_DNA.
DR   PIR; JQ0741; JQ0741.
DR   RefSeq; NP_420271.1; NC_002696.2.
DR   RefSeq; WP_010919334.1; NC_002696.2.
DR   AlphaFoldDB; P21297; -.
DR   SMR; P21297; -.
DR   STRING; 190650.CC_1458; -.
DR   EnsemblBacteria; AAK23439; AAK23439; CC_1458.
DR   KEGG; ccr:CC_1458; -.
DR   PATRIC; fig|190650.5.peg.1484; -.
DR   eggNOG; COG5443; Bacteria.
DR   HOGENOM; CLU_130913_0_0_5; -.
DR   OMA; QLMYIDE; -.
DR   BioCyc; CAULO:CC1458-MON; -.
DR   Proteomes; UP000001816; Chromosome.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:InterPro.
DR   GO; GO:1902209; P:negative regulation of bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00783; FlbT; 1.
DR   InterPro; IPR009967; Flagellum_FlbT.
DR   Pfam; PF07378; FlbT; 1.
DR   PIRSF; PIRSF009533; FlbT; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Reference proteome; Repressor; RNA-binding.
FT   CHAIN           1..141
FT                   /note="Flagellum biosynthesis repressor protein FlbT"
FT                   /id="PRO_0000217155"
SQ   SEQUENCE   141 AA;  15863 MW;  F31A0B6D8714A7DC CRC64;
     MPLKLSLKPG EKFVLNGAVV QNGDRRGVLV LQNKASVLRE KDIMQPDQVT TPARHIYFPV
     MMMYLDEVGA EKFYEEFATR LNEFMGVVRN PVVLQDCIAI SKHVMAREYY KALMLSRKLI
     EYEDERLGHV SSGVSAGGDA G