ID   FLB_CAMJ8               Reviewed;         576 AA.
AC   P22252; A8FN17;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 4.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Flagellin B;
GN   Name=flaB; OrderedLocusNames=C8J_1255;
OS   Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC
OS   11828).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=407148;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2211662; DOI=10.1016/s0021-9258(18)38234-6;
RA   Nuijten P.J., van Asten F.J., Gaastra W., van der Zeijst B.A.M.;
RT   "Structural and functional analysis of two Campylobacter jejuni flagellin
RT   genes.";
RL   J. Biol. Chem. 265:17798-17804(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=81116 / NCTC 11828;
RX   PubMed=17873037; DOI=10.1128/jb.01404-07;
RA   Pearson B.M., Gaskin D.J.H., Segers R.P.A.M., Wells J.M., Nuijten P.J.M.,
RA   van Vliet A.H.M.;
RT   "The complete genome sequence of Campylobacter jejuni strain 81116
RT   (NCTC11828).";
RL   J. Bacteriol. 189:8402-8403(2007).
RN   [3]
RP   INTERACTION WITH FLIW, SUBUNIT, SUBCELLULAR LOCATION, AND DISRUPTION
RP   PHENOTYPE.
RC   STRAIN=81116 / NCTC 11828;
RX   PubMed=27353476; DOI=10.1111/mmi.13455;
RA   Radomska K.A., Ordonez S.R., Woesten M.M., Wagenaar J.A., van Putten J.P.;
RT   "Feedback control of Campylobacter jejuni flagellin levels through
RT   reciprocal binding of FliW to flagellin and the global regulator CsrA.";
RL   Mol. Microbiol. 102:207-220(2016).
RN   [4]
RP   INTERACTION WITH FLIS, SUBUNIT, AND SUBCELLULAR LOCATION.
RC   STRAIN=81116 / NCTC 11828;
RX   PubMed=28659885; DOI=10.3389/fmicb.2017.01060;
RA   Radomska K.A., Woesten M.M.S.M., Ordonez S.R., Wagenaar J.A.,
RA   van Putten J.P.M.;
RT   "Importance of Campylobacter jejuni FliS and FliW in flagella biogenesis
RT   and flagellin secretion.";
RL   Front. Microbiol. 8:1060-1060(2017).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella.
CC   -!- SUBUNIT: Heteromer of FlaA and FlaB (Probable). Interacts with FliW
CC       (PubMed:27353476). Interacts with FliS (PubMed:27353476).
CC       {ECO:0000269|PubMed:27353476, ECO:0000269|PubMed:28659885,
CC       ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27353476,
CC       ECO:0000269|PubMed:28659885}. Bacterial flagellum.
CC   -!- DISRUPTION PHENOTYPE: In a double flaA-flaB deletion, cells grow faster
CC       and are non-motile, flagellar filaments are non-existent
CC       (PubMed:27353476). {ECO:0000269|PubMed:27353476}.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; J05635; AAA23025.1; -; Genomic_DNA.
DR   EMBL; CP000814; ABV52854.1; -; Genomic_DNA.
DR   PIR; B39228; B39228.
DR   RefSeq; WP_012006751.1; NC_009839.1.
DR   AlphaFoldDB; P22252; -.
DR   SMR; P22252; -.
DR   KEGG; cju:C8J_1255; -.
DR   HOGENOM; CLU_011142_7_1_7; -.
DR   OMA; ITHNQIA; -.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF07196; Flagellin_IN; 2.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   1: Evidence at protein level;
KW   Bacterial flagellum; Secreted.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..576
FT                   /note="Flagellin B"
FT                   /id="PRO_0000182597"
FT   CONFLICT        564
FT                   /note="A -> R (in Ref. 1; AAA23025)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   576 AA;  59774 MW;  04436E970F5C4F01 CRC64;
     MGFRINTNIG ALNAHANSVV NSNELDKSLS RLSSGLRINS AADDASGMAI ADSLRSQAAT
     LGQAINNGND AIGILQTADK AMDEQLKILD TIKTKATQAA QDGQSLKTRT MLQADINRLM
     EELDNIANTT SFNGKQLLSG NFTNQEFQIG ASSNQTIKAT IGATQSSKIG VTRFETGAQS
     FTSGVVGLTI KNYNGIEDFK FDNVVISTSV GTGLGALAEE INKSADKTGV RATYDVKTTG
     VYAIKEGTTS QDFAINGVVI GQINYKDGDN NGQLVSAINA VKDTTGVQAS KDENGKLVLT
     SADGRGIKIT GDIGVGSGIL ANQKENYGRL SLVKNDGRDI NISGTNLSAI GMGTTDMISQ
     SSVSLRESKG QISATNADAM GFNSYKGGGK FVFTQNVSSI SAFMSAQGSG FSRGSGFSVG
     SGKNLSVGLS QGIQIISSAA SMSNTYVVSA GSGFSSGSGN SQFAALKTTA ANTTDETAGV
     TTLKGAMAVM DIAETAITNL DQIRADIGSV QNQLQVTINN ITVTQVNVKA AESTIRDVDF
     ASESANFSKY NILAQSGSYA MSQANAVQQN VLKLLQ