ID   FLGA_ECOLI              Reviewed;         219 AA.
AC   P75933;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 135.
DE   RecName: Full=Flagella basal body P-ring formation protein FlgA;
DE   Flags: Precursor;
GN   Name=flgA; OrderedLocusNames=b1072, JW1059;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in the assembly process of the P-ring formation. It
CC       may associate with FlgF on the rod constituting a structure essential
CC       for the P-ring assembly or may act as a modulator protein for the P-
CC       ring assembly.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FlgA family. {ECO:0000305}.
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DR   EMBL; U00096; AAC74156.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35880.1; -; Genomic_DNA.
DR   PIR; E64850; E64850.
DR   RefSeq; NP_415590.1; NC_000913.3.
DR   RefSeq; WP_000905458.1; NZ_SSZK01000053.1.
DR   AlphaFoldDB; P75933; -.
DR   SMR; P75933; -.
DR   BioGRID; 4260070; 182.
DR   IntAct; P75933; 2.
DR   STRING; 511145.b1072; -.
DR   PaxDb; P75933; -.
DR   PRIDE; P75933; -.
DR   EnsemblBacteria; AAC74156; AAC74156; b1072.
DR   EnsemblBacteria; BAA35880; BAA35880; BAA35880.
DR   GeneID; 946300; -.
DR   KEGG; ecj:JW1059; -.
DR   KEGG; eco:b1072; -.
DR   PATRIC; fig|1411691.4.peg.1196; -.
DR   EchoBASE; EB4160; -.
DR   eggNOG; COG1261; Bacteria.
DR   HOGENOM; CLU_070510_2_0_6; -.
DR   InParanoid; P75933; -.
DR   OMA; RYEIQVN; -.
DR   PhylomeDB; P75933; -.
DR   BioCyc; EcoCyc:G357-MON; -.
DR   PRO; PR:P75933; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IMP:EcoCyc.
DR   InterPro; IPR017585; Flag_basal_body_FlgA_C.
DR   InterPro; IPR039246; Flagellar_FlgA.
DR   InterPro; IPR013974; SAF.
DR   PANTHER; PTHR36307; PTHR36307; 1.
DR   Pfam; PF13144; ChapFlgA; 1.
DR   SMART; SM00858; SAF; 1.
DR   TIGRFAMs; TIGR03170; flgA_cterm; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /note="Or 26"
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..219
FT                   /note="Flagella basal body P-ring formation protein FlgA"
FT                   /id="PRO_0000009341"
SQ   SEQUENCE   219 AA;  23519 MW;  69D8E6252E9ED73A CRC64;
     MLIIKRSVAI IAILFSPLST ASNLTSQLHN FFSAQLAGVS DEVRVSIRTA PNLLPPCEQP
     LLSMSNNSRL WGNVNVLARC GNDKRYLQVN VQATGNYVVA AMPIARGGKL EAGNVKLKRG
     RLDTLPPRTV LDINQLVDAI SLRDLSPDQP IQLTQFRQAW RVKAGQRVNV IASGDGFSAN
     AEGQALNNAA VAQNARVRMV SGQVVSGVVD ADGNILINL