FLGB_ECOLI
ID FLGB_ECOLI Reviewed; 138 AA.
AC P0ABW9; P75934;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Flagellar basal body rod protein FlgB;
DE AltName: Full=Putative proximal rod protein;
GN Name=flgB; Synonyms=fla FII, flbA; OrderedLocusNames=b1073, JW1060;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP DISRUPTION PHENOTYPE.
RC STRAIN=K12 / BW25113;
RX PubMed=17122336; DOI=10.1128/jb.01294-06;
RA Inoue T., Shingaki R., Hirose S., Waki K., Mori H., Fukui K.;
RT "Genome-wide screening of genes required for swarming motility in
RT Escherichia coli K-12.";
RL J. Bacteriol. 189:950-957(2007).
CC -!- FUNCTION: Structural component of flagellum, the bacterial motility
CC apparatus. Part of the rod structure of flagellar basal body (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC organelle and consists of a number of rings mounted on a central rod.
CC In Gram-negative bacteria, at least four rings, L, P, S and M are
CC present, whereas Gram-positive bacteria lack the L and P rings. The rod
CC consists of about 26 subunits of FlgG in the distal portion, and FlgB,
CC FlgC and FlgF build up the proximal portion of the rod with about 6
CC subunits each. Rod assembly occurs by export via the flagellum-specific
CC pathway of its constituent proteins and by their incorporation into the
CC rod structure in the probable order of FlgB, FlgC, FlgF and FlgG.
CC Another protein, FliE, also assembles onto the stable rod structure (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body {ECO:0000250}.
CC -!- DISRUPTION PHENOTYPE: Strongly repressed swarming and swimming.
CC {ECO:0000269|PubMed:17122336}.
CC -!- SIMILARITY: Belongs to the flagella basal body rod proteins family.
CC {ECO:0000305}.
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DR EMBL; U00096; AAC74157.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35881.1; -; Genomic_DNA.
DR PIR; F64850; F64850.
DR RefSeq; NP_415591.1; NC_000913.3.
DR RefSeq; WP_000884702.1; NZ_STEB01000016.1.
DR AlphaFoldDB; P0ABW9; -.
DR SMR; P0ABW9; -.
DR BioGRID; 4261281; 15.
DR ComplexPortal; CPX-5887; Flagellar basal-body rod complex.
DR IntAct; P0ABW9; 6.
DR STRING; 511145.b1073; -.
DR PaxDb; P0ABW9; -.
DR PRIDE; P0ABW9; -.
DR EnsemblBacteria; AAC74157; AAC74157; b1073.
DR EnsemblBacteria; BAA35881; BAA35881; BAA35881.
DR GeneID; 66670660; -.
DR GeneID; 945678; -.
DR KEGG; ecj:JW1060; -.
DR KEGG; eco:b1073; -.
DR PATRIC; fig|1411691.4.peg.1195; -.
DR EchoBASE; EB4014; -.
DR eggNOG; COG1815; Bacteria.
DR HOGENOM; CLU_125463_1_0_6; -.
DR InParanoid; P0ABW9; -.
DR OMA; GHMARND; -.
DR PhylomeDB; P0ABW9; -.
DR BioCyc; EcoCyc:FLGB-FLAGELLAR-MOTOR-ROD-PROTEIN; -.
DR PRO; PR:P0ABW9; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009288; C:bacterial-type flagellum; IMP:EcoCyc.
DR GO; GO:0030694; C:bacterial-type flagellum basal body, rod; TAS:EcoCyc.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IC:ComplexPortal.
DR GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IBA:GO_Central.
DR GO; GO:0006935; P:chemotaxis; IC:ComplexPortal.
DR InterPro; IPR001444; Flag_bb_rod_N.
DR InterPro; IPR019776; Flagellar_basal_body_rod_CS.
DR InterPro; IPR006300; FlgB.
DR PANTHER; PTHR30435:SF12; PTHR30435:SF12; 1.
DR Pfam; PF00460; Flg_bb_rod; 1.
DR PIRSF; PIRSF002889; Rod_FlgB; 1.
DR TIGRFAMs; TIGR01396; FlgB; 1.
DR PROSITE; PS00588; FLAGELLA_BB_ROD; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Reference proteome.
FT CHAIN 1..138
FT /note="Flagellar basal body rod protein FlgB"
FT /id="PRO_0000180790"
SQ SEQUENCE 138 AA; 15240 MW; D7889ABCD42B657D CRC64;
MLDKLDAALR FQQEALNLRA QRQEVLAANI ANADTPGYQA RDIDFASELK KVMQRGRDAT
SVVALTMTST QHIPAQALTP PTAELQYRIP DQPSLDGNTV DMDRERTQFA DNSLQYQMSL
SALSGQIKGM MNVLQSGN
