FLGD_SALTY
ID FLGD_SALTY Reviewed; 232 AA.
AC P0A1I9; P16321;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Basal-body rod modification protein FlgD;
GN Name=flgD; Synonyms=fla FIV, flaV; OrderedLocusNames=STM1176;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=8049271; DOI=10.1016/0167-4781(94)90202-x;
RA Kutsukake K., Doi H.;
RT "Nucleotide sequence of the flgD gene of Salmonella typhimurium which is
RT essential for flagellar hook formation.";
RL Biochim. Biophys. Acta 1218:443-446(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 223-232.
RX PubMed=2193164; DOI=10.1016/s0022-2836(05)80266-9;
RA Homma M., Derosier D.J., Macnab R.M.;
RT "Flagellar hook and hook-associated proteins of Salmonella typhimurium and
RT their relationship to other axial components of the flagellum.";
RL J. Mol. Biol. 213:819-832(1990).
RN [4]
RP CHARACTERIZATION.
RX PubMed=8157595; DOI=10.1128/jb.176.8.2272-2281.1994;
RA Ohnishi K., Ohto Y., Aizawa S., Macnab R.M., Lino T.;
RT "FlgD is a scaffolding protein needed for flagellar hook assembly in
RT Salmonella typhimurium.";
RL J. Bacteriol. 176:2272-2281(1994).
CC -!- FUNCTION: Required for flagellar hook formation. May act as a
CC scaffolding protein.
CC -!- INTERACTION:
CC P0A1I9; P26416: fliK; NbExp=2; IntAct=EBI-6408673, EBI-6408664;
CC -!- SIMILARITY: Belongs to the FlgD family. {ECO:0000305}.
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DR EMBL; D25293; BAA04982.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20106.1; -; Genomic_DNA.
DR EMBL; X51737; CAA36021.1; -; Genomic_DNA.
DR PIR; S47641; S47641.
DR RefSeq; NP_460147.1; NC_003197.2.
DR RefSeq; WP_000020450.1; NC_003197.2.
DR PDB; 7BHQ; EM; 3.20 A; A/B/C/D/E=1-232.
DR PDB; 7EH9; X-ray; 2.20 A; A/B=74-232.
DR PDB; 7EHA; X-ray; 3.30 A; A/B/C/D/E=1-232.
DR PDBsum; 7BHQ; -.
DR PDBsum; 7EH9; -.
DR PDBsum; 7EHA; -.
DR AlphaFoldDB; P0A1I9; -.
DR SMR; P0A1I9; -.
DR IntAct; P0A1I9; 1.
DR STRING; 99287.STM1176; -.
DR PaxDb; P0A1I9; -.
DR DNASU; 1252694; -.
DR EnsemblBacteria; AAL20106; AAL20106; STM1176.
DR GeneID; 1252694; -.
DR KEGG; stm:STM1176; -.
DR PATRIC; fig|99287.12.peg.1244; -.
DR HOGENOM; CLU_047535_0_0_6; -.
DR OMA; STYAHVT; -.
DR PhylomeDB; P0A1I9; -.
DR BioCyc; SENT99287:STM1176-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IBA:GO_Central.
DR InterPro; IPR005648; FlgD.
DR InterPro; IPR025965; FlgD_Ig.
DR InterPro; IPR025963; FLgD_Tudor.
DR Pfam; PF03963; FlgD; 1.
DR Pfam; PF13860; FlgD_ig; 1.
DR Pfam; PF13861; FLgD_tudor; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Bacterial flagellum biogenesis; Reference proteome.
FT CHAIN 1..232
FT /note="Basal-body rod modification protein FlgD"
FT /id="PRO_0000180814"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT HELIX 33..46
FT /evidence="ECO:0007829|PDB:7BHQ"
FT STRAND 49..51
FT /evidence="ECO:0007829|PDB:7BHQ"
FT HELIX 58..90
FT /evidence="ECO:0007829|PDB:7BHQ"
FT HELIX 91..94
FT /evidence="ECO:0007829|PDB:7EH9"
FT TURN 95..98
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 99..104
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 107..111
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 125..131
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 133..141
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 147..152
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 158..163
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 172..174
FT /evidence="ECO:0007829|PDB:7BHQ"
FT STRAND 177..187
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 191..193
FT /evidence="ECO:0007829|PDB:7BHQ"
FT STRAND 195..202
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 205..207
FT /evidence="ECO:0007829|PDB:7BHQ"
FT STRAND 210..212
FT /evidence="ECO:0007829|PDB:7EH9"
FT STRAND 214..216
FT /evidence="ECO:0007829|PDB:7BHQ"
FT HELIX 218..220
FT /evidence="ECO:0007829|PDB:7EH9"
FT HELIX 225..227
FT /evidence="ECO:0007829|PDB:7EH9"
SQ SEQUENCE 232 AA; 23988 MW; 5CD481F25EDFF966 CRC64;
MSIAVNMNDP TNTGVKTTTG SGSMTGSNAA DLQSSFLTLL VAQLKNQDPT NPLQNNELTT
QLAQISTVSG IEKLNTTLGA ISGQIDNSQS LQATTLIGHG VMVPGTTILA GKGAEEGAVT
STTPFGVELQ QPADKVTATI TDKDGRVVRT LEIGELRAGV HTFTWDGKQT DGTTVPNGSY
NIAITASNGG TQLVAQPLQF ALVQGVTKGS NGNLLDLGTY GTTTLDEVRQ II
