ID   FLGE_TREPA              Reviewed;         463 AA.
AC   O07884;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Flagellar hook protein FlgE;
GN   Name=flgE; OrderedLocusNames=TP_0727;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8755894; DOI=10.1128/jb.178.15.4628-4634.1996;
RA   Limberger R.J., Slivienski L.L., El-Afandi M.C.T., Dantuono L.A.;
RT   "Organization, transcription, and expression of the 5' region of the fla
RT   operon of Treponema phagedenis and Treponema pallidum.";
RL   J. Bacteriol. 178:4628-4634(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the flagella basal body rod proteins family.
CC       {ECO:0000305}.
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DR   EMBL; U28219; AAB61251.1; -; Genomic_DNA.
DR   EMBL; AE000520; AAC65692.1; -; Genomic_DNA.
DR   PIR; C71292; C71292.
DR   RefSeq; WP_010882172.1; NC_021490.2.
DR   AlphaFoldDB; O07884; -.
DR   SMR; O07884; -.
DR   IntAct; O07884; 7.
DR   STRING; 243276.TPANIC_0727; -.
DR   EnsemblBacteria; AAC65692; AAC65692; TP_0727.
DR   GeneID; 57879251; -.
DR   KEGG; tpa:TP_0727; -.
DR   eggNOG; COG1749; Bacteria.
DR   HOGENOM; CLU_013687_2_4_12; -.
DR   OMA; GLQNHQT; -.
DR   OrthoDB; 704242at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.98.20; -; 1.
DR   InterPro; IPR011491; Falgellar_hook_FlgE.
DR   InterPro; IPR037058; Falgellar_hook_FlgE_sf.
DR   InterPro; IPR001444; Flag_bb_rod_N.
DR   InterPro; IPR019776; Flagellar_basal_body_rod_CS.
DR   InterPro; IPR020013; Flagellar_FlgE/F/G.
DR   InterPro; IPR010930; Flg_bb/hook_C_dom.
DR   InterPro; IPR037925; FlgE/F/G-like.
DR   Pfam; PF07559; FlaE; 1.
DR   Pfam; PF00460; Flg_bb_rod; 1.
DR   Pfam; PF06429; Flg_bbr_C; 1.
DR   SUPFAM; SSF117143; SSF117143; 1.
DR   TIGRFAMs; TIGR03506; FlgEFG_subfam; 1.
DR   PROSITE; PS00588; FLAGELLA_BB_ROD; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Reference proteome.
FT   CHAIN           1..463
FT                   /note="Flagellar hook protein FlgE"
FT                   /id="PRO_0000180832"
SQ   SEQUENCE   463 AA;  49179 MW;  947C4C413B36E7A8 CRC64;
     MMRSLFSGVS GMQNHQTRMD VIGNNVANVN TTGFKRGRVN FQDLISQQLS AAARPNEEVG
     GVNPKEVGLG VLIASIDTVH TQGALQTTGI NTDVSIQGSG FFVLKSGEKT FFTRAGAFGV
     DNAGTLVNPA NGMRVQGWMA QDVAGERLIN SSAQTQDLVI PIGQKIDAQQ TSTVHYACNL
     DKRLPELAAD ANEADVRKST WTTDFQVYDS FGQQHTLQIN FSRVPGTNNQ WQATVAVDPG
     TEVDTQTRVG VGTSDGAANT FIVNFDNFGH LASVTDTAGN VTGPTGQVLL EASYDVVGAN
     PDDAGQVTRH AFTLNLGEIG TARNTITQFA ERSTTKAYRQ DGYAMGYLEN FKIDQSGVIT
     GVYSNGVSQD IGQLALAGFA NQGGLEKAGE NTYVQSNNSG IANISTSGVM GKGKLIAGTL
     EMSNVDLTDQ FTDMIITQKG FQAGAKTIQT SDTMLDTVLS LKR