FLGH_CAUVC
ID FLGH_CAUVC Reviewed; 244 AA.
AC P22606;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 2.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Flagellar L-ring protein;
DE AltName: Full=Basal body L-ring protein;
DE Flags: Precursor;
GN Name=flgH; Synonyms=flbN; OrderedLocusNames=CC_2066;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=2211524; DOI=10.1128/jb.172.10.6066-6076.1990;
RA Dingwall A., Gober J.W., Shapiro L.;
RT "Identification of a Caulobacter basal body structural gene and a cis-
RT acting site required for activation of transcription.";
RL J. Bacteriol. 172:6066-6076(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- FUNCTION: Assembles around the rod to form the L-ring and probably
CC protects the motor/basal body from shearing forces during rotation.
CC -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC organelle and consists of five rings (E,L,P,S, and M) mounted on a
CC central rod.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC {ECO:0000250}. Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FlgH family. {ECO:0000305}.
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DR EMBL; M37270; AAA23035.1; -; Genomic_DNA.
DR EMBL; AE005673; AAK24037.1; -; Genomic_DNA.
DR PIR; A36148; A36148.
DR PIR; A87505; A87505.
DR RefSeq; NP_420869.1; NC_002696.2.
DR RefSeq; WP_010919927.1; NC_002696.2.
DR AlphaFoldDB; P22606; -.
DR SMR; P22606; -.
DR STRING; 190650.CC_2066; -.
DR EnsemblBacteria; AAK24037; AAK24037; CC_2066.
DR KEGG; ccr:CC_2066; -.
DR PATRIC; fig|190650.5.peg.2085; -.
DR eggNOG; COG2063; Bacteria.
DR HOGENOM; CLU_069313_1_2_5; -.
DR OMA; ITQQPMT; -.
DR BioCyc; CAULO:CC2066-MON; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0009427; C:bacterial-type flagellum basal body, distal rod, L ring; IEA:InterPro.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR HAMAP; MF_00415; FlgH; 1.
DR InterPro; IPR000527; Flag_Lring.
DR PANTHER; PTHR34933; PTHR34933; 1.
DR Pfam; PF02107; FlgH; 1.
DR PRINTS; PR01008; FLGLRINGFLGH.
PE 3: Inferred from homology;
KW Bacterial flagellum; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW Reference proteome; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..244
FT /note="Flagellar L-ring protein"
FT /id="PRO_0000009438"
FT LIPID 19
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 19
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
FT CONFLICT 57..69
FT /note="AASANSLWRVGAR -> RFGQLAVAGRGP (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 95
FT /note="S -> R (in Ref. 1; AAA23035)"
FT /evidence="ECO:0000305"
FT CONFLICT 98..99
FT /note="NA -> KP (in Ref. 1; AAA23035)"
FT /evidence="ECO:0000305"
FT CONFLICT 113
FT /note="P -> R (in Ref. 1; AAA23035)"
FT /evidence="ECO:0000305"
FT CONFLICT 150
FT /note="Missing (in Ref. 1; AAA23035)"
FT /evidence="ECO:0000305"
FT CONFLICT 167
FT /note="V -> L (in Ref. 1; AAA23035)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 244 AA; 25525 MW; 7C08BEACF1D5BA30 CRC64;
MRRPAILAAA VLLAPLAACS TVKEAVKGPD LAPVGYPAPL APMQQQYVSA REPAPQAASA
NSLWRVGARA FFNDQRASRV GDIVTVMIDI DDSASTKNAT NSSRTANMKA GVPHLLGMES
SLGKFLPGGF DPASALETNS TTTNAGSGGV SRSEKISLTI AAVVSQVLPN GNMVIQGTQE
VRTNAELRQL TVAGIVRPED ISSANTIRHT QIAEARISYG GRGDISRVQK TPAGQSLVEK
FSPF
