FLGH_HELPY
ID FLGH_HELPY Reviewed; 237 AA.
AC O25092;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Flagellar L-ring protein;
DE AltName: Full=Basal body L-ring protein;
DE Flags: Precursor;
GN Name=flgH; OrderedLocusNames=HP_0325;
OS Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=85962;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700392 / 26695;
RX PubMed=9252185; DOI=10.1038/41483;
RA Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT "The complete genome sequence of the gastric pathogen Helicobacter
RT pylori.";
RL Nature 388:539-547(1997).
CC -!- FUNCTION: Assembles around the rod to form the L-ring and probably
CC protects the motor/basal body from shearing forces during rotation.
CC {ECO:0000250}.
CC -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC organelle and consists of four rings (L,P,S, and M) mounted on a
CC central rod. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}. Bacterial
CC flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FlgH family. {ECO:0000305}.
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DR EMBL; AE000511; AAD07392.1; -; Genomic_DNA.
DR PIR; E64560; E64560.
DR RefSeq; NP_207123.1; NC_000915.1.
DR RefSeq; WP_000709989.1; NC_018939.1.
DR AlphaFoldDB; O25092; -.
DR SMR; O25092; -.
DR DIP; DIP-3206N; -.
DR IntAct; O25092; 13.
DR MINT; O25092; -.
DR STRING; 85962.C694_01645; -.
DR PaxDb; O25092; -.
DR DNASU; 900196; -.
DR EnsemblBacteria; AAD07392; AAD07392; HP_0325.
DR KEGG; hpy:HP_0325; -.
DR PATRIC; fig|85962.47.peg.348; -.
DR eggNOG; COG2063; Bacteria.
DR OMA; ITQQPMT; -.
DR PhylomeDB; O25092; -.
DR Proteomes; UP000000429; Chromosome.
DR GO; GO:0009427; C:bacterial-type flagellum basal body, distal rod, L ring; IEA:InterPro.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR HAMAP; MF_00415; FlgH; 1.
DR InterPro; IPR000527; Flag_Lring.
DR PANTHER; PTHR34933; PTHR34933; 1.
DR Pfam; PF02107; FlgH; 1.
DR PRINTS; PR01008; FLGLRINGFLGH.
PE 3: Inferred from homology;
KW Bacterial flagellum; Cell outer membrane; Membrane; Reference proteome;
KW Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..237
FT /note="Flagellar L-ring protein"
FT /id="PRO_0000009451"
FT REGION 87..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 237 AA; 26469 MW; C0D1E43DDE42F6F9 CRC64;
MKKALYLGAV AFSVAFSMAS ANEPKIDFNP PNYVEETPSK EFIPELNKLG SLFGQGERPL
FADRRAMKPN DLITIIVSEK ASANYSSSKD YKSASGGNST PPRLTYNGLD ERKKKEAEYL
DDKNNYNFTK SSNNTNFKGG GSQKKSEDLE IVLSARIIKV LENGNYFIYG NKEVLVDGEK
QILKVSGVIR PYDIERNNTI QSKFLADAKI EYTNLGHLSD SNKKKFAADA METQMPY
