FLGH_SALTY
ID FLGH_SALTY Reviewed; 232 AA.
AC P0A1N8; P15929;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Flagellar L-ring protein;
DE AltName: Full=Basal body L-ring protein;
DE Flags: Precursor;
GN Name=flgH; Synonyms=fla FVIII, flaY; OrderedLocusNames=STM1180;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2544561; DOI=10.1128/jb.171.7.3890-3900.1989;
RA Jones C.J., Homma M., Macnab R.M.;
RT "L-, P-, and M-ring proteins of the flagellar basal body of Salmonella
RT typhimurium: gene sequences and deduced protein sequences.";
RL J. Bacteriol. 171:3890-3900(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-7.
RX PubMed=2129540; DOI=10.1016/0022-2836(90)90365-s;
RA Homma M., Kutsukake K., Hasebe M., Iino T., Macnab R.M.;
RT "FlgB, FlgC, FlgF and FlgG. A family of structurally related proteins in
RT the flagellar basal body of Salmonella typhimurium.";
RL J. Mol. Biol. 211:465-477(1990).
CC -!- FUNCTION: Assembles around the rod to form the L-ring and probably
CC protects the motor/basal body from shearing forces during rotation.
CC -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC organelle and consists of four rings (L,P,S, and M) mounted on a
CC central rod.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC {ECO:0000250}. Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FlgH family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M24466; AAA27068.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20110.1; -; Genomic_DNA.
DR EMBL; X52094; CAA36315.1; -; Genomic_DNA.
DR PIR; A32887; A30930.
DR RefSeq; NP_460151.1; NC_003197.2.
DR RefSeq; WP_001174897.1; NC_003197.2.
DR PDB; 7BGL; EM; 2.20 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z=1-232.
DR PDB; 7CBL; EM; 2.80 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z=1-232.
DR PDB; 7CGO; EM; 3.90 A; AA/AB/AC/AD/AE/AF/AG/AH/AI/AJ/AK/AL/AM/AN/AO/AP/AQ/AR/AS/AT/AU/AV/AW/AX/AY/AZ=1-232.
DR PDB; 7CLR; EM; 3.50 A; a/b/c/d/e/f/g/h/i/j/k/l/m/n/o/p/q/r/s/t/u/v/w/x/y/z=1-232.
DR PDBsum; 7BGL; -.
DR PDBsum; 7CBL; -.
DR PDBsum; 7CGO; -.
DR PDBsum; 7CLR; -.
DR AlphaFoldDB; P0A1N8; -.
DR SMR; P0A1N8; -.
DR STRING; 99287.STM1180; -.
DR PaxDb; P0A1N8; -.
DR DNASU; 1252698; -.
DR EnsemblBacteria; AAL20110; AAL20110; STM1180.
DR GeneID; 1252698; -.
DR KEGG; stm:STM1180; -.
DR PATRIC; fig|99287.12.peg.1248; -.
DR HOGENOM; CLU_069313_0_0_6; -.
DR OMA; ITQQPMT; -.
DR PhylomeDB; P0A1N8; -.
DR BioCyc; SENT99287:STM1180-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0009427; C:bacterial-type flagellum basal body, distal rod, L ring; IEA:InterPro.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR HAMAP; MF_00415; FlgH; 1.
DR InterPro; IPR000527; Flag_Lring.
DR PANTHER; PTHR34933; PTHR34933; 1.
DR Pfam; PF02107; FlgH; 1.
DR PRINTS; PR01008; FLGLRINGFLGH.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Bacterial flagellum; Cell outer membrane; Lipoprotein;
KW Membrane; Palmitate; Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..232
FT /note="Flagellar L-ring protein"
FT /id="PRO_0000009471"
FT LIPID 22
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 22
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 232 AA; 24709 MW; A555EEF7BAB55E36 CRC64;
MQKYALHAYP VMALMVATLT GCAWIPAKPL VQGATTAQPI PGPVPVANGS IFQSAQPINY
GYQPLFEDRR PRNIGDTLTI VLQENVSASK SSSANASRDG KTSFGFDTVP RYLQGLFGNS
RADMEASGGN SFNGKGGANA SNTFSGTLTV TVDQVLANGN LHVVGEKQIA INQGTEFIRF
SGVVNPRTIS GSNSVPSTQV ADARIEYVGN GYINEAQNMG WLQRFFLNLS PM
