ID   AKTIP_AEDAE             Reviewed;         230 AA.
AC   Q17PP1;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Protein crossbronx homolog;
GN   ORFNames=AAEL000265;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA   Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA   Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA   Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA   Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA   El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA   Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA   Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA   Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA   Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA   Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA   Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. FTS
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC   -!- CAUTION: Lacks the conserved Cys residue necessary for ubiquitin-
CC       conjugating enzyme E2 activity. {ECO:0000305}.
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DR   EMBL; CH477190; EAT48710.1; -; Genomic_DNA.
DR   RefSeq; XP_001654780.1; XM_001654730.1.
DR   AlphaFoldDB; Q17PP1; -.
DR   SMR; Q17PP1; -.
DR   STRING; 7159.AAEL000265-PA; -.
DR   GeneID; 5573752; -.
DR   KEGG; aag:5573752; -.
DR   VEuPathDB; VectorBase:AAEL000265; -.
DR   eggNOG; KOG0429; Eukaryota.
DR   HOGENOM; CLU_083049_1_0_1; -.
DR   InParanoid; Q17PP1; -.
DR   OMA; QVLKYMQ; -.
DR   OrthoDB; 1226125at2759; -.
DR   PhylomeDB; Q17PP1; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..230
FT                   /note="Protein crossbronx homolog"
FT                   /id="PRO_0000379026"
FT   DOMAIN          14..168
FT                   /note="UBC core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
SQ   SEQUENCE   230 AA;  26447 MW;  17CD24324DD4B2B9 CRC64;
     MTLDSYDKLL GTVLQEYKIL SEYKRLQNED LGGLYVIPSF ENSFLWFGVI FVRSGPYKDG
     VFRFTVSLPD KFPNDATVPT VVFQSETFHP LIDPYNGTLE LAEAFPKWKS GENHVWQLLK
     FIQYIFASFD EYMSLAEQSA NNVAYELYGQ NRPEFLRKVE ECVRLGQSRL YDPAPVQDRN
     YIVFDRFDRE THGPVLESLK QGKANEVTTP PSSGLSWVKE GVFQPLSKQG