ID   AKTIP_ANOGA             Reviewed;         228 AA.
AC   Q7PRH1;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Protein crossbronx homolog;
GN   ORFNames=AGAP010478;
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST;
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA   Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA   Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA   Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA   Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA   Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA   Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA   Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA   Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA   Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA   McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA   O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA   Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA   Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA   Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA   Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA   Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA   Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA   Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. FTS
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC   -!- CAUTION: Lacks the conserved Cys residue necessary for ubiquitin-
CC       conjugating enzyme E2 activity. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAAB01008849; EAA07209.4; -; Genomic_DNA.
DR   RefSeq; XP_311466.3; XM_311466.3.
DR   AlphaFoldDB; Q7PRH1; -.
DR   SMR; Q7PRH1; -.
DR   STRING; 7165.AGAP010478-PA; -.
DR   PaxDb; Q7PRH1; -.
DR   GeneID; 1272603; -.
DR   KEGG; aga:AgaP_AGAP010478; -.
DR   CTD; 1272603; -.
DR   VEuPathDB; VectorBase:AGAP010478; -.
DR   eggNOG; KOG0429; Eukaryota.
DR   HOGENOM; CLU_083049_1_0_1; -.
DR   InParanoid; Q7PRH1; -.
DR   OMA; QVLKYMQ; -.
DR   OrthoDB; 1226125at2759; -.
DR   PhylomeDB; Q7PRH1; -.
DR   Proteomes; UP000007062; Chromosome 3L.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..228
FT                   /note="Protein crossbronx homolog"
FT                   /id="PRO_0000379027"
FT   DOMAIN          14..168
FT                   /note="UBC core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
SQ   SEQUENCE   228 AA;  26394 MW;  9D4F2F535D85198A CRC64;
     MTLDANDKLL EAVLQEYKIL AEYERLQSED LGGIYVTPSY ENPFLWFGVI FVRSGMYKDG
     VFRFTISLPN RFPNDSTVPV VAFQSDVFHP MVNPSDGVLN LSDTFPKWQS GDSHIWQMLK
     FVQFILQNLD DHTIPSEHVV NNEAYQLLME NRAEFLLRVE QCVEDSQRKL YDLPAQPDRF
     YICFDRFNPD VHGPVLQSMK EDKPTEVTTP PSSGLSWVRK GFYQPLSK